[HTML][HTML] Kiss1 is differentially regulated in male and female mice by the homeodomain transcription factor VAX1

SN Lavalle, T Chou, J Hernandez, NCP Naing… - Molecular and cellular …, 2021 - Elsevier
Regulation of Kiss1 transcription is crucial to the development and function of the
reproductive axis. The homeodomain transcription factor, ventral anterior homeobox 1 …

BAX-Dependent and BAX-Independent Regulation of Kiss1 Neuron Development in Mice

SJ Semaan, EK Murray, MC Poling, S Dhamija… - …, 2010 - academic.oup.com
The Kiss1 gene and its product kisspeptin are important regulators of reproduction. In
rodents, Kiss1 is expressed in the hypothalamic arcuate (ARC) and anteroventral …

Epigenetic regulation of Kiss1 gene expression mediating estrogen-positive feedback action in the mouse brain

J Tomikawa, Y Uenoyama, M Ozawa… - Proceedings of the …, 2012 - National Acad Sciences
This study aims to determine the epigenetic mechanism regulating Kiss1 gene expression in
the anteroventral periventricular nucleus (AVPV) to understand the mechanism underlying …

Assessment of Epigenetic Contributions to Sexually-Dimorphic Kiss1 Expression in the Anteroventral Periventricular Nucleus of Mice

SJ Semaan, S Dhamija, J Kim, EC Ku… - …, 2012 - academic.oup.com
The Kiss1 gene, which encodes kisspeptin and is critical for reproduction, is sexually
differentiated in the hypothalamic anteroventral periventricular (AVPV)/rostral periventricular …

Developmental GnRH Signaling Is Not Required for Sexual Differentiation of Kisspeptin Neurons but Is Needed for Maximal Kiss1 Gene Expression in Adult Females

J Kim, KP Tolson, S Dhamija, AS Kauffman - Endocrinology, 2013 - academic.oup.com
Kisspeptin, encoded by Kiss1, stimulates reproduction. In rodents, one Kiss1 population
resides in the hypothalamic anterior ventral periventricular nucleus and neighboring rostral …

Retinoblastoma binding protein 7 is involved in Kiss1 mRNA upregulation in rodents

K Horihata, N Inoue, Y Uenoyama… - … of Reproduction and …, 2020 - jstage.jst.go.jp
Kisspeptin, encoded by Kiss1, is essential for reproduction in mammals. Kiss1 expression is
regulated by estrogen via histone acetylation in the Kiss1 promotor region. Thus, elucidation …

An alternative transcription start site yields estrogen-unresponsive Kiss1 mRNA transcripts in the hypothalamus of prepubertal female rats

JM Castellano, H Wright, SR Ojeda, A Lomniczi - Neuroendocrinology, 2014 - karger.com
The importance of the Kiss1 gene in the control of reproductive development is well
documented. However, much less is known about the transcriptional regulation of Kiss1 …

Transcriptional regulation of the human KiSS1 gene

JK Mueller, A Dietzel, A Lomniczi, A Loche… - Molecular and cellular …, 2011 - Elsevier
Kisspeptin, the product of the KiSS1 gene, has emerged as a key component of the
mechanism by which the hypothalamus controls puberty and reproductive development. It …

Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse

ML Gottsch, SM Popa, JK Lawhorn, J Qiu… - …, 2011 - academic.oup.com
Neurons that produce kisspeptin play a critical role in reproduction. However, understanding
the molecular physiology of kisspeptin neurons has been limited by the lack of an in vivo …

ESR2 Is Essential for Gonadotropin-Induced Kiss1 Expression in Granulosa Cells

VP Chakravarthi, V Khristi, S Ghosh… - …, 2018 - academic.oup.com
Hypothalamic expression of Kiss1 plays an essential role in the onset of puberty, gonadal
development, and ovulation. Estrogens regulate the expression of Kiss1 in the …