Background: Debate continues about the comparative benefits and harms of first-generation
antipsychotics (FGAs) and second-generation antipsychotics (SGAs) in treating …

Background Because of the debate about whether second-generation antipsychotic drugs
are better than first-generation antipsychotic drugs, we did a meta-analysis of randomised …

Objective: To comprehensively review the 2 recent and large antipsychotic effectiveness
trials for treatment of schizophrenia: the United Kingdom's Cost Utility of the Latest …

Background: The Intercontinental Schizophrenia Outpatient Health Outcomes (IC-SOHO)
study was designed to provide information regarding use and outcome of antipsychotic …

Rationale There are many psychotropic drugs available for treatment of schizophrenia. The
clinician's choice of the most effective first-line antipsychotic treatment for patients with …

The initial enthusiasm about the second-generation or atypical antipsychotic drugs soon
changed into criticism and debate, culminating in the controversial CATIE (Clinical …

Objective: Whether there are differences in efficacy among second-generation
antipsychotics in the treatment of schizophrenia is a matter of heated debate. The authors …

Background: Antipsychotic medications are conventionally divided into two groups: First-
generation and second-generation antipsychotics (FGAs and SGAs). There is a …

Background The question of which antipsychotic drug should be preferred for the treatment
of schizophrenia is controversial, and conventional pairwise meta-analyses cannot provide …

We conducted a systematic review and meta-analysis of randomized controlled trials that
compared second-generation antipsychotic (SGA) drugs with placebo in schizophrenic …