Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins

T Herdegen, JD Leah - Brain research reviews, 1998 - Elsevier
This article reviews findings up to the end of 1997 about the inducible transcription factors
(ITFs) c-Jun, JunB, JunD, c-Fos, FosB, Fra-1, Fra-2, Krox-20 (Egr-2) and Krox-24 (NGFI-A …

Basal expression of the inducible transcription factors c‐Jun, JunB, JunD, c‐Fos, FosB, and Krox‐24 in the adult rat brain

T Herdegen, K Kovary, A Buhl, R Bravo… - Journal of …, 1995 - Wiley Online Library
Abstract Jun, Fos, and Krox proteins are inducible transcription factors contributing to the
control of gene expression. The elucidation of their individual expression patterns in the …

Neuronal expression of AP-1 proteins in excitotoxic-neurodegenerative disorders and following nerve fiber lesions

P Gass, T Herdegen - Progress in neurobiology, 1995 - Elsevier
This review tries to survey the expression patterns of inducible transcription factors (ITFs) of
the Jun (c-Jun, JunB, JunD) and Fos (c-Fos, FosB, Fra) families as well as of zinc finger …

JUN, FOS, KROX, and CREB transcription factor proteins in the rat cortex: basal expression and induction by spreading depression and epileptic seizures

T Herdegen, J Sandkühler, P Gass… - Journal of …, 1993 - Wiley Online Library
The expression of the nuclear c‐JUN, JUN B, JUN D, c‐FOS, FOS B, KROX‐24, and CREB
transcription factors was investigated in the cortex of adult rats by immunocytochemistry. The …

Fos-Jun and the primary genomic response in the nervous system: possible physiological role and pathophysiological significance

JP Doucet, SP Squinto, NG Bazan - Molecular neurobiology, 1990 - Springer
Introduction The Primary Genomic Response Stimulus-Transcription Coupling The Fos-Jun
Paradigm Second Messenger Stimulation of fos and jun Permutations of Fos-Jun …

Role of the AP-1 transcription factor c-Jun in developing, adult and injured brain

G Raivich, A Behrens - Progress in neurobiology, 2006 - Elsevier
The transcription factor activator protein-1 (AP-1) consists of a variety of dimers composed of
members of the Jun and Fos families of proteins. However, it is the up-regulation of c-jun that …

The role of Jun transcription factor expression and phosphorylation in neuronal differentiation, neuronal cell death, and plastic adaptationsin vivo

KH Schlingensiepen, F Wollnik, M Kunst… - Cellular and molecular …, 1994 - Springer
To investigate the role of the Jun transcription factors in neuronal differentiation,
programmed neuronal cell death, and neuronal plasticity, we used phosphorothioate …

A Dominant-Negative Inhibitor of CREB Reveals that It Is a General Mediator of Stimulus-Dependent Transcription of c-fos

S Ahn, M Olive, S Aggarwal, D Krylov… - … and cellular biology, 1998 - Taylor & Francis
Several studies have characterized the upstream regulatory region of c-fos, and identified
cis-acting elements termed the cyclic AMP (cAMP) response elements (CREs) that are …

Activation of immediate early genes and memory formation

W Tischmeyer, R Grimm - Cellular and Molecular Life Sciences CMLS, 1999 - Springer
Long-term plastic changes in the brain, including those supporting memory formation, are
assumed to depend on permanent functional alterations in neuronal cells that require …

Fos: an immediate‐early transcription factor in neurons

T Curran, JI Morgan - Journal of neurobiology, 1995 - Wiley Online Library
In the past several years a great deal of evidence has accumulated linking neuronal
activation events to the regulation of gene expression. We have pursued an analysis of c‐fos …