Clustered DNA damage is related to the biological effects of ionizing radiation. However, its
precise yield and complexity (ie, number of lesions per damaged site) in vivo remain …

Ionizing radiation produces clustered DNA damage that contains two or more lesions in 10–
20 bp. It is believed that the complexity of clustered damage (ie, the number of lesions per …

Ionizing radiation induces multiple damaged sites (clustered damage) together with isolated
lesions in DNA. Clustered damage consists of closely spaced lesions within a few helical …

Clustered DNA damage (locally multiply damaged site) is thought to be a critical lesion
caused by ionizing radiation, and high LET radiation such as heavy ion particles is believed …

Photons, such as X-or γ-rays, induce DNA damage (distributed throughout the nucleus) as a
result of low-density energy deposition. In contrast, particle irradiation with high linear …

After living cells are exposed to ionizing radiation, a variety of chemical modifications of DNA
are induced either directly by ionization of DNA or indirectly through interactions with water …

Clustered DNA damages—two or more closely spaced damages (strand breaks, abasic
sites, or oxidized bases) on opposing strands—are suspects as critical lesions producing …

Abstract Sutherland, BM, Bennett, PV, Sutherland, JC and Laval, J. Clustered DNA
Damages Induced by X Rays in Human Cells. Radiat. Res. 157, 611–616 (2002). Although …

Cells exposed to densely ionizing radiation (high-LET) experience more severe biological
damage than do cells exposed to sparsely ionizing radiation (low-LET). The prevailing …

Clustered DNA damages are induced by ionizing radiation and are defined as two or more
lesions within one or two helical turns. The aim of this study was to investigate the induction …