[HTML][HTML] Immunological aspects of approved MS therapeutics
Multiple sclerosis (MS) is the most common neurological immune-mediated disease leading
to disability in young adults. The outcome of the disease is unpredictable, and over time …
to disability in young adults. The outcome of the disease is unpredictable, and over time …
[HTML][HTML] Multiple sclerosis: immunopathology and treatment update
N Dargahi, M Katsara, T Tselios, ME Androutsou… - Brain sciences, 2017 - mdpi.com
The treatment of multiple sclerosis (MS) has changed over the last 20 years. All
immunotherapeutic drugs target relapsing remitting MS (RRMS) and it still remains a …
immunotherapeutic drugs target relapsing remitting MS (RRMS) and it still remains a …
Risks and risk management in modern multiple sclerosis immunotherapeutic treatment
L Klotz, J Havla, N Schwab, R Hohlfeld… - Therapeutic …, 2019 - journals.sagepub.com
In recent years, there has been a paradigm shift in the treatment of multiple sclerosis (MS)
owing to the approval of a number of new drugs with very distinct mechanisms of action. All …
owing to the approval of a number of new drugs with very distinct mechanisms of action. All …
Multiple sclerosis: pathogenesis and treatment
I Loma, R Heyman - Current neuropharmacology, 2011 - ingentaconnect.com
Multiple sclerosis (MS) is a chronic inflammatory autoimmune demyelinating disease of the
central nervous system. It affects approximately 400,000 people in the United States and …
central nervous system. It affects approximately 400,000 people in the United States and …
[HTML][HTML] Safety of newer disease modifying therapies in multiple sclerosis
G Jalkh, R Abi Nahed, G Macaron, M Rensel - Vaccines, 2020 - mdpi.com
In the past decade, the therapeutic arsenal for multiple sclerosis has expanded greatly.
Newer more potent disease modifying therapies (DMTs) with varying mechanisms of actions …
Newer more potent disease modifying therapies (DMTs) with varying mechanisms of actions …
Basic and escalating immunomodulatory treatments in multiple sclerosis: current therapeutic recommendations
Multiple Sclerosis Therapy Consensus Group … - Journal of …, 2008 - Springer
This review updates and extends earlier Consensus Reports related to current basic and
escalating immunomodulatory treatments in multiple sclerosis (MS). The recent literature …
escalating immunomodulatory treatments in multiple sclerosis (MS). The recent literature …
Novel therapeutic strategies for multiple sclerosis—a multifaceted adversary
RS Lopez-Diego, HL Weiner - Nature Reviews Drug Discovery, 2008 - nature.com
Therapeutic strategies for multiple sclerosis have radically changed in the past 15 years.
Five regulatory-approved immunomodulatory agents are reasonably effective in the …
Five regulatory-approved immunomodulatory agents are reasonably effective in the …
Immunopathology of multiple sclerosis
CA Dendrou, L Fugger, MA Friese - Nature Reviews Immunology, 2015 - nature.com
Two decades of clinical experience with immunomodulatory treatments for multiple sclerosis
point to distinct immunological pathways that drive disease relapses and progression. In …
point to distinct immunological pathways that drive disease relapses and progression. In …
Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis
Multiple sclerosis (MS) is the most common inflammatory disorder of the central nervous
system (CNS) in young adults. When MS is not treated, it leads to irreversible and severe …
system (CNS) in young adults. When MS is not treated, it leads to irreversible and severe …
Immune reconstitution therapies: concepts for durable remission in multiple sclerosis
New so-called immune reconstitution therapies (IRTs) have the potential to induce long-term
or even permanent drug-free remission in people with multiple sclerosis (MS). These …
or even permanent drug-free remission in people with multiple sclerosis (MS). These …