A structural scaffold embedding brain cells and vasculature is known as extracellular matrix
(ECM). The physical appearance of ECM in the central nervous system (CNS) ranges from a …

The extracellular matrix (ECM) occupies the space between neurons and glial cells and
accounts for 10%–20% of the total volume of the brain. During CNS development, the ECM …

The extracellular matrix (ECM) of the brain has important roles in regulating synaptic
function and plasticity. A juvenile ECM supports the wiring of neuronal networks …

The integrity of the central nervous system (CNS) matrix is crucial for its proper function.
Loss of the lattice-like structure compromise synaptic stability and can lead to the disruption …

Synapses are specialized structures that mediate rapid and efficient signal transmission
between neurons and are surrounded by glial cells. Astrocytes develop an intimate …

Extracellular matrix (ECM) molecules that are released by neurons and glial cells form
perineuronal nets (PNNs) and modulate many neuronal and glial functions. PNNs, whose …

The extracellular matrix (ECM) of the central nervous system (CNS) occupies a large part of
the neural tissue. It serves a variety of functions ranging from support of cell migration and …

There is increasing interest in defining the location, content, and role of extracellular matrix
(ECM) components in brain structure and function during development, aging, injury, and …

Perineuronal nets (PNNs) are reticular structures that surround the cell body of many
neurones, and extend along their dendrites. They are considered to be a specialized …

The extracellular matrix (ECM) of the central nervous system is well recognized as a
migration and diffusion barrier that allows for the trapping and presentation of growth factors …