Proteome of synaptosome‐associated proteins in spinal cord dorsal horn after peripheral nerve injury

OV Singh, M Yaster, JT Xu, Y Guan, X Guan… - …, 2009 - Wiley Online Library
Peripheral nerve injury may lead to neuroadaptive changes of cellular signals in spinal cord
that are thought to contribute to central mechanisms underlying neuropathic pain. Here we …

[HTML][HTML] Proteomic analysis of the dorsal spinal cord in the mouse model of spared nerve injury-induced neuropathic pain

E Park, J Ahn, S Jeon, H Cho, K Chung… - Journal of Biomedical …, 2017 - ncbi.nlm.nih.gov
Peripheral nerve injury often causes neuropathic pain and is associated with changes in the
expression of numerous proteins in the dorsal horn of the spinal cord. To date, proteomic …

Proteomics study of neuropathic and nonneuropathic dorsal root ganglia: altered protein regulation following segmental spinal nerve ligation injury

N Komori, N Takemori, HK Kim, A Singh… - Physiological …, 2007 - journals.physiology.org
Peripheral nerve injury is often followed by the development of severe neuropathic pain.
Nerve degeneration accompanied by inflammatory mediators is thought to play a role in …

Proteomics of neuropathic pain: proteins and signaling pathways affected in a rat model

P Sui, H Watanabe, MH Ossipov… - Journal of proteome …, 2014 - ACS Publications
The myriad proteins may be involved in the mechanisms underlying the development and
maintenance of neuropathic pain, an extremely disabling condition that originates from …

[HTML][HTML] CSF proteomics of secondary phase spinal cord injury in human subjects: perturbed molecular pathways post injury

MB Sengupta, M Basu, S Iswarari, KK Mukhopadhyay… - Plos one, 2014 - journals.plos.org
Recovery of sensory and motor functions following traumatic spinal cord injury (SCI) is
dependent on injury severity. Here we identified 49 proteins from cerebrospinal fluid (CSF) …

Proteomic profiling of proteins in rat spinal cord induced by contusion injury

X Yan, J Liu, Z Luo, Q Ding, X Mao, M Yan… - Neurochemistry …, 2010 - Elsevier
It is widely accepted that mechanical injury to spinal cord can cause nervous system
dysfunction, which leads to the loss of movement and sensation. However, the exact …

An optimal protocol to analyze the rat spinal cord proteome

F Gil-Dones, S Alonso-Orgaz, G Avila… - Biomarker …, 2009 - journals.sagepub.com
Since the function of the spinal cord depends on the proteins found there, better defing the
normal Spinal Cord Proteome is an important and challenging task. Although brain and …

Signaling proteins in spinal parenchyma and dorsal root ganglion in rat with spinal injury-induced spasticity

HK Skalnikova, R Navarro, S Marsala, R Hrabakova… - Journal of …, 2013 - Elsevier
Abstract Development of progressive muscle spasticity resulting from spinal traumatic injury
can be mediated by loss of local segmental inhibition and/or by an increased sensory …

[HTML][HTML] Differential neuroproteomic and systems biology analysis of spinal cord injury

A Moghieb, HM Bramlett, JH Das, Z Yang… - Molecular & Cellular …, 2016 - ASBMB
Acute spinal cord injury (SCI) is a devastating condition with many consequences and no
known effective treatment. Although it is quite easy to diagnose traumatic SCI, the …

Proteome analysis of up‐regulated proteins in the rat spinal cord induced by transection injury

Q Ding, Z Wu, Y Guo, C Zhao, Y Jia, F Kong… - …, 2006 - Wiley Online Library
The inability of the CNS to regenerate in adult mammals propels us to reveal associated
proteins involved in the injured CNS. In this paper, either thoracic laminectomy (as sham …