Idiopathic pulmonary fibrosis (IPF) is a chronic and lethal lung disease characterized by
progressive lung scarring. This study aims to elucidate the role of the E3 ubiquitin ligase …

Interstitial pulmonary fibrosis (IPF) is a severe progressive lung disease with limited
therapeutic options and poor prognosis. Initially, we found the downregulated level of neural …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease
characterized by patchy scarring of the distal lung with limited therapeutic options and poor …

Ubiquitination-mediated protein degradation is associated with the development of
pulmonary fibrosis. We and others have shown that Nedd4L plays anti-inflammatory and anti …

Rationale: The differentiation of fibroblasts into myofibroblasts is a cardinal feature of
idiopathic pulmonary fibrosis (IPF). The transcription factor Yin Yang 1 (YY1) plays a role in …

Pulmonary fibrosis is a chronic, progressive lung disease associated with lung damage and
scarring. The pathological mechanism causing pulmonary fibrosis remains unknown …

Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease that is associated with
aberrant activation of TGF-β, myofibroblast differentiation, and abnormal extracellular matrix …

Idiopahtic pulmonary firbosis (IPF) is a severe lung disease of unknown etiology with a poor
prognosis and limited therapeutic options. In this study, we characterized a mouse model …

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with high mortality.
Active TGFβ1 is considered central to the pathogenesis of IPF. A major mechanism of TGFβ1 …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and highly lethal lung disease
with unknown etiology and poor prognosis. IPF patients die within 2 years after diagnosis …