[PDF][PDF] The Role of L-selectin in Tuberculosis and HIV Coinfection: Implications for Disease Diagnosis and Management

EI Obeagu, GU Obeagu - Elite Journal of Public Health, 2024 - researchgate.net
Tuberculosis (TB) and human immunodeficiency virus (HIV) coinfection pose significant
challenges for disease diagnosis and management, with immune dysfunction playing a …

[PDF][PDF] Modulation of L-selectin Expression in Tuberculosis-HIV Coinfection: Implications for Disease Control

EI Obeagu, EC Onuoha - Elite Journal of Public Health, 2024 - researchgate.net
Tuberculosis (TB) and human immunodeficiency virus (HIV) coinfection presents a complex
challenge in global health, characterized by heightened disease severity and therapeutic …

[PDF][PDF] Understanding Immune Cell Trafficking in Tuberculosis-HIV Coinfection: The Role of L-selectin Pathways

EI Obeagu, GU Obeagu - Elite Journal of Immunology, 2024 - researchgate.net
Tuberculosis (TB) and human immunodeficiency virus (HIV) coinfection pose significant
challenges to global health, with dysregulated immune cell trafficking contributing to disease …

[PDF][PDF] Exploring the Role of L-selectin in HIV-related Immune Exhaustion: Insights and Therapeutic Implications

EI Obeagu, GU Obeagu - Elite Journal of HIV, 2024 - researchgate.net
HIV infection leads to progressive immune dysfunction characterized by T cell exhaustion, a
state of functional impairment and loss of effector functions. L-selectin, a key adhesion …

[PDF][PDF] L-selectin and HIV-Induced Immune Cell Trafficking: Implications for Pathogenesis and Therapeutic Strategies

EI Obeagu, GU Obeagu - Elite Journal of Laboratory Medicine, 2024 - researchgate.net
HIV infection is characterized by dysregulated immune cell trafficking, contributing to chronic
immune activation, inflammation, and disease progression. L-selectin, a key adhesion …

[PDF][PDF] P-Selectin and Immune Activation in HIV: Clinical Implications

EI Obeagu, GU Obeagu - Elite Journal of Health Science, 2024 - academia.edu
P-Selectin, a pivotal cell adhesion molecule expressed on activated endothelial cells and
platelets, plays a critical role in immune activation and inflammation. In the context of human …

[PDF][PDF] P-Selectin Expression in HIV-Associated Coagulopathy: Implications for Treatment

EI Obeagu, GU Obeagu - Elite Journal of Haematology, 2024 - researchgate.net
HIV infection is associated with a heightened risk of coagulopathy, encompassing
thrombosis, hemorrhage, and endothelial dysfunction, which significantly impact disease …

Up-regulation of VCAM-1 and differential expansion of β integrin-expressing T lymphocytes are associated with immunity to pulmonary Mycobacterium tuberculosis …

CG Feng, WJ Britton, U Palendira, NL Groat… - The Journal of …, 2000 - journals.aai.org
Immune responses rely on an intricate system of adhesion molecules to coordinate the
homing and retention of lymphocytes in both secondary lymphoid tissues and at sites of …

[HTML][HTML] The C-Type Lectin Receptor DC-SIGN Has an Anti-Inflammatory Role in Human M(IL-4) Macrophages in Response to Mycobacterium tuberculosis

G Lugo-Villarino, A Troegeler, L Balboa… - Frontiers in …, 2018 - frontiersin.org
DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-
surface marker of interleukin 4 (IL-4)-activated human macrophages [M (IL-4)], which …

[HTML][HTML] L-selectin enhanced T cells improve the efficacy of cancer immunotherapy

HA Watson, RRP Durairaj, J Ohme… - Frontiers in …, 2019 - frontiersin.org
The homing molecule, L-selectin (CD62L), is commonly used as a T cell activation marker,
since expression is downregulated following engagement of the T cell receptor. Studies in …