Cell-based therapy in prophylaxis and treatment of chronic graft-versus-host disease

M Doglio, RE Crossland, AC Alho, O Penack… - Frontiers in …, 2022 - frontiersin.org
Hematopoietic allogeneic stem cell transplantation (allo-SCT) is a curative option for
patients with hematological malignancies. However, due to disparities in major and minor …

Advance in targeted immunotherapy for graft-versus-host disease

L Zhang, J Yu, W Wei - Frontiers in immunology, 2018 - frontiersin.org
Graft-versus-host disease (GVHD) is a serious and deadly complication of patients, who
undergo hematopoietic stem cell transplantation (HSCT). Despite prophylactic treatment …

Thinking out of the box—new approaches to controlling GVHD

F Baron, S Humblet-Baron, G Ehx, S Servais… - Current hematologic …, 2014 - Springer
Graft-versus-host disease (GVHD) remains a major limitation of allogeneic hematopoietic
cell transplantation (allo-HCT). Despite major advances in the understanding of GVHD …

Highlighting the interaction between immunomodulatory properties of mesenchymal stem cells and signaling pathways contribute to Graft Versus Host Disease …

R Mirfakhraie, MT Ardakani, A Hajifathali, S Karami… - Transplant …, 2022 - Elsevier
Background Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) has been
increasingly used as a therapeutic approach for hematological malignancies. Several …

Recent advances on cellular therapies and immune modulators for graft-versus-host disease

P Filippini, S Rutella - Expert Review of Clinical Immunology, 2014 - Taylor & Francis
The efficacy of allogeneic hematopoietic stem cell transplantation is counterbalanced by the
occurrence of life-threatening immune-mediated complications, such as graft-versus-host …

Can we prevent or treat graft-versus-host disease with cellular-therapy?

MF Zahid, HM Lazarus, O Ringdén, JA Barrett, RP Gale… - Blood reviews, 2020 - Elsevier
Acute and chronic graft-versus-host disease (Gv HD) are the most important causes of
treatment-related morbidity and mortality after allogeneic hematopoietic cell transplants for …

The potential of cytotherapeutics in hematologic reconstitution and in the treatment and prophylaxis of graft-versus-host disease. Chapter II: emerging transformational …

AA Vertès - Regenerative Medicine, 2015 - Taylor & Francis
Hematopoietic stem cell transplantation (HSCT) is a life-saving treatment for inherited
anemias, immunodeficiencies or hematologic malignancies. A major complication of allo …

Mesenchymal stem cells for treatment and prevention of graft-versus-host disease after allogeneic hematopoietic cell transplantation

T Toubai, S Paczesny, Y Shono… - Current stem cell …, 2009 - ingentaconnect.com
Allogeneic hematopoietic cell transplantation (allo-HCT) is an effective therapy for
hematological malignancies and inherited diseases. However, acute graft-versus-host …

Mesenchymal stem cells as cellular immunotherapeutics in allogeneic hematopoietic stem cell transplantation

C Papewalis, D Topolar, B Götz, S Schönberger… - … Stem Cells-Basics and …, 2013 - Springer
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment option
in hematopoietic disorders, immunodeficiencies and leukemia. To date graft-versus-host …

Mesenchymal stem cells for the treatment and prevention of graft-versus-host disease: experiments and practice

N Kim, KI Im, JY Lim, EJ Jeon, YS Nam, EJ Kim… - Annals of …, 2013 - Springer
Mesenchymal stem cells (MSCs) have emerged as a therapeutic approach in a range of
medical fields, including regenerative medicine, cancer, autoimmune diseases, and …