The RNA helicase DDX39A binds a conserved structure in Chikungunya virus RNA to control infection
Alphaviruses are a large group of re-emerging arthropod-borne RNA viruses. The compact
viral RNA genomes harbor diverse structures that facilitate replication. These structures can …
viral RNA genomes harbor diverse structures that facilitate replication. These structures can …
DDX56 binds to chikungunya virus RNA to control infection
ABSTRACT DEAD box RNA helicases regulate diverse facets of RNA biology. Proteins of
this family carry out essential cellular functions, and emerging literature is revealing …
this family carry out essential cellular functions, and emerging literature is revealing …
The host DHX9 DExH-box helicase is recruited to chikungunya virus replication complexes for optimal genomic RNA translation
R Matkovic, E Bernard, S Fontanel, P Eldin… - Journal of …, 2019 - Am Soc Microbiol
Beyond their role in cellular RNA metabolism, DExD/H-box RNA helicases are hijacked by
various RNA viruses in order to assist replication of the viral genome. Here, we identify the …
various RNA viruses in order to assist replication of the viral genome. Here, we identify the …
Cellular DDX21 RNA helicase inhibits influenza A virus replication but is counteracted by the viral NS1 protein
Influenza A virus RNA synthesis is catalyzed by the viral polymerase comprised of the PA,
PB1, and PB2 proteins. We show that the host DDX21 RNA helicase restricts influenza A …
PB1, and PB2 proteins. We show that the host DDX21 RNA helicase restricts influenza A …
Structural basis of human helicase DDX21 in RNA binding, unwinding, and antiviral signal activation
Z Chen, Z Li, X Hu, F Xie, S Kuang, B Zhan… - Advanced …, 2020 - Wiley Online Library
RNA helicase DDX21 plays vital roles in ribosomal RNA biogenesis, transcription, and the
regulation of host innate immunity during virus infection. How DDX21 recognizes and …
regulation of host innate immunity during virus infection. How DDX21 recognizes and …
DEAD-box helicase DDX25 is a negative regulator of type I interferon pathway and facilitates RNA virus infection
T Feng, T Sun, G Li, W Pan, K Wang… - Frontiers in Cellular and …, 2017 - frontiersin.org
Dengue is a mosquito-borne viral disease that rapidly spread in tropic and subtropic area in
recent years. DEAD (Glu-Asp-Ala-Glu)-box RNA helicases have been reported to play …
recent years. DEAD (Glu-Asp-Ala-Glu)-box RNA helicases have been reported to play …
Structural insights into RNA recognition by the Chikungunya virus nsP2 helicase
Chikungunya virus (CHIKV) is transmitted to humans through mosquitoes and causes
Chikungunya fever. Nonstructural protein 2 (nsP2) exhibits the protease and RNA helicase …
Chikungunya fever. Nonstructural protein 2 (nsP2) exhibits the protease and RNA helicase …
RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity
F Valiente‐Echeverría, MA Hermoso… - Reviews in medical …, 2015 - Wiley Online Library
Summary Asp‐Glu‐Ala‐Asp (DEAD)‐box polypeptide 3, or DDX3, belongs to the DEAD‐box
family of ATP‐dependent RNA helicases and is known to play different roles in RNA …
family of ATP‐dependent RNA helicases and is known to play different roles in RNA …
DDX5 RNA helicases: emerging roles in viral infection
W Cheng, G Chen, H Jia, X He, Z Jing - International journal of molecular …, 2018 - mdpi.com
Asp-Glu-Ala-Asp (DEAD)-box polypeptide 5 (DDX5), also called p68, is a prototypical
member of the large ATP-dependent RNA helicases family and is known to participate in all …
member of the large ATP-dependent RNA helicases family and is known to participate in all …
Targeting host DEAD-box RNA helicase DDX3X for treating viral infections
PT Winnard Jr, F Vesuna, V Raman - Antiviral research, 2021 - Elsevier
Abstract DDX3X or DDX3, a member of the DEAD (asp, glu, ala, asp) box RNA helicase
family of proteins, is a multifunctional protein, which is usurped by several viruses and is vital …
family of proteins, is a multifunctional protein, which is usurped by several viruses and is vital …