The current evidence on statin use and prostate cancer prevention: are we there yet?

MA Alfaqih, EH Allott, RJ Hamilton… - Nature Reviews …, 2017 - nature.com
An increasing amount of data supports an inverse association between statin use and
cancer risk. The findings for prostate cancer, particularly advanced disease, are the most …

Review of recent evidence in support of a role for statins in the prevention of prostate cancer

RJ Hamilton, SJ Freedland - Current opinion in urology, 2008 - journals.lww.com
The exact association between statin medication use and prostate cancer, and whether this
association is causal in nature, remains unclear. Recent evidence, however, is encouraging …

Statins and prostate cancer prevention: where we are now, and future directions

TJ Murtola, T Visakorpi, J Lahtela, H Syvälä… - Nature Clinical Practice …, 2008 - nature.com
Statins are cholesterol-lowering drugs that are widely used to prevent and treat
atherosclerotic cardiovascular disease. Recent research from both in vitro and in vivo …

Statin use and the risk of prostate cancer: A metaanalysis of 6 randomized clinical trials and 13 observational studies

S Bonovas, K Filioussi… - International Journal of …, 2008 - Wiley Online Library
Statins have been suggested to prevent prostate cancer. Our aim was to examine statin use
in relation to both total prostate cancer and the more clinically important advanced prostate …

[HTML][HTML] Statins and prostate cancer—hype or hope? The epidemiological perspective

EL Craig, KH Stopsack, E Evergren, LZ Penn… - Prostate cancer and …, 2022 - nature.com
Background Men using cholesterol-lowering statin medications have been found to have
lower risks of both advanced and fatal prostate cancer in multiple registry-based studies and …

Statin use and incident prostate cancer risk: does the statin brand matter? A population-based cohort study

A Lustman, S Nakar, AD Cohen, S Vinker - Prostate cancer and …, 2014 - nature.com
Background: Statins have known anticarcinogenic effects; evidence for long-term statin use
as effective chemoprevention for prostate cancer is inconsistent. Methods: We conducted a …

Statins and prostate cancer: molecular and clinical aspects

G Papadopoulos, D Delakas, L Nakopoulou… - European Journal of …, 2011 - Elsevier
The field of the potential applications of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)
reductase inhibitors (statins) beyond their unambiguous cardiovascular beneficial effects is …

[HTML][HTML] Statin use and risk of prostate cancer: a meta-analysis of observational studies

D Bansal, K Undela, S D'Cruz, F Schifano - 2012 - journals.plos.org
Background Emerging evidence suggests that statins may decrease the risk of cancers.
However, available evidence on prostate cancer (PCa) is conflicting. We therefore examined …

Statin drugs and risk of advanced prostate cancer

EA Platz, MF Leitzmann, K Visvanathan… - Journal of the …, 2006 - academic.oup.com
Background: Statins are commonly used cholesterol-lowering drugs that have proapoptotic
and antimetastatic activities that could affect cancer risk or progression. Results from …

Statin use in prostate cancer: an update

MA Babcook, A Joshi, JA Montellano… - Nutrition and …, 2016 - journals.sagepub.com
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, known as statins, are
commonly prescribed for the treatment of hypercholesterolemia and cardiovascular disease …