Chronic pancreatitis: diagnosis, classification, and new genetic developments

B Etemad, DC Whitcomb - Gastroenterology, 2001 - Elsevier
The utilization of recent advances in molecular and genomic technologies and progress in
pancreatic imaging techniques provided remarkable insight into genetic, environmental …

Chronic pancreatitis

MJ DiMagno, EP DiMagno - Current opinion in gastroenterology, 2006 - journals.lww.com
Researchers this past year have further characterized genetic, molecular and clinical
aspects of chronic pancreatitis. Advancing the understanding of fibrogenesis, mechanisms …

Chronic pancreatitis: an international draft consensus proposal for a new mechanistic definition

DC Whitcomb, L Frulloni, P Garg, JB Greer… - Pancreatology, 2016 - Elsevier
Background A definition of chronic pancreatitis (CP) is needed for diagnosis and
distinguishing CP from other disorders. Previous definitions focused on morphology …

Chronic pancreatitis: managing a difficult disease

PA Hart, DL Conwell - Official journal of the American College of …, 2020 - journals.lww.com
Chronic pancreatitis is characterized by progressive, irreversible morphologic and functional
changes that are most commonly attributed to environmental insults, particularly when there …

Genetics of pancreatitis

J LaRusch, DC Whitcomb - Current opinion in gastroenterology, 2011 - journals.lww.com
Pancreatic diseases have a strong genetic component. Rather than a classic Mendelian
disorder, recurrent acute and chronic pancreatitis represents truly complex diseases with the …

[HTML][HTML] Pathophysiology of chronic pancreatitis

C Brock, LM Nielsen, D Lelic… - World journal of …, 2013 - ncbi.nlm.nih.gov
Chronic pancreatitis (CP) is an inflammatory disease of the pancreas characterized by
progressive fibrotic destruction of the pancreatic secretory parenchyma. Despite the …

[HTML][HTML] Review of idiopathic pancreatitis

JK Lee, R Enns - World journal of gastroenterology: WJG, 2007 - ncbi.nlm.nih.gov
Recent advances in understanding of pancreatitis and advances in technology have
uncovered the veils of idiopathic pancreatitis to a point where a thorough history and …

Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy

H Witt, MV Apte, V Keim, JS Wilson - Gastroenterology, 2007 - Elsevier
Chronic pancreatitis (CP) is characterized by progressive pancreatic damage that eventually
results in significant impairment of exocrine as well as endocrine functions of the gland. In …

Mechanisms of disease: advances in understanding the mechanisms leading to chronic pancreatitis

DC Whitcomb - Nature Clinical Practice Gastroenterology & …, 2004 - nature.com
Chronic pancreatitis remains a challenging and frustrating clinical problem. In the past few
years, however, advances in genetic and immunologic research have spawned new insights …

Chronic pancreatitis

J Kleeff, DC Whitcomb, T Shimosegawa… - Nature reviews Disease …, 2017 - nature.com
Chronic pancreatitis is defined as a pathological fibro-inflammatory syndrome of the
pancreas in individuals with genetic, environmental and/or other risk factors who develop …