Genetic testing in prostate cancer management: Considerations informing primary care
VN Giri, TM Morgan, DS Morris… - CA: a cancer journal …, 2022 - Wiley Online Library
Inherited genetic mutations can significantly increase the risk for prostate cancer (PC), may
be associated with aggressive disease and poorer outcomes, and can have hereditary …
be associated with aggressive disease and poorer outcomes, and can have hereditary …
Germline testing and genetic counselling in prostate cancer
J Russo, VN Giri - Nature Reviews Urology, 2022 - nature.com
Genetic testing for prostate cancer is rapidly growing and is increasingly being driven by
precision medicine. Rates of germline pathogenic variants have been reported in up to 15 …
precision medicine. Rates of germline pathogenic variants have been reported in up to 15 …
Practical considerations and challenges for germline genetic testing in patients with prostate cancer: recommendations from the germline genetics working group of …
BM Szymaniak, LA Facchini, VN Giri… - JCO oncology …, 2020 - ascopubs.org
Germline genetic testing is now routinely recommended for patients with prostate cancer
(PCa) because of expanded guidelines and options for targeted treatments. However …
(PCa) because of expanded guidelines and options for targeted treatments. However …
Germline and somatic mutations in prostate cancer for the clinician
It is increasingly important for clinicians involved in the management of prostate cancer to
understand the relevance of heritable (germline) mutations that, for select patients, affect …
understand the relevance of heritable (germline) mutations that, for select patients, affect …
Evolving intersection between inherited cancer genetics and therapeutic clinical trials in prostate cancer: a white paper from the Germline Genetics Working Group of …
MI Carlo, VN Giri, CJ Paller, W Abida… - JCO precision …, 2018 - ascopubs.org
Purpose Advances in germline genetics, and related therapeutic opportunities, present new
opportunities and challenges in prostate cancer. The Prostate Cancer Clinical Trials …
opportunities and challenges in prostate cancer. The Prostate Cancer Clinical Trials …
Germline genetic testing in advanced prostate cancer; practices and barriers: survey results from the Germline Genetics Working Group of the Prostate Cancer Clinical …
Background Germline genetic testing increasingly identifies advanced prostate cancer
(PCa) patients who are candidates for precision therapies. The Prostate Cancer Clinical …
(PCa) patients who are candidates for precision therapies. The Prostate Cancer Clinical …
Barriers and facilitators of germline genetic evaluation for prostate cancer
S Loeb, R Li, T Sanchez Nolasco, N Byrne… - The …, 2021 - Wiley Online Library
Background Genetic counseling and germline testing have an increasingly important role for
patients with prostate cancer (PCa); however, recent data suggests they are underutilized …
patients with prostate cancer (PCa); however, recent data suggests they are underutilized …
Clinical implications of germline testing in newly diagnosed prostate cancer
S Loeb, VN Giri - European urology oncology, 2021 - Elsevier
Context Germline testing (GT) is increasingly impacting prostate cancer (PCa) management
and screening, with direct effects in urology, medical oncology, and radiation oncology. The …
and screening, with direct effects in urology, medical oncology, and radiation oncology. The …
Germline genetic testing for inherited prostate cancer in practice: Implications for genetic testing, precision therapy, and cascade testing
VN Giri, SE Hegarty, C Hyatt, E O'Leary, J Garcia… - The …, 2019 - Wiley Online Library
Background Genetic testing capability and guidelines are rapidly expanding to assess
inherited prostate cancer (PCA). Clinical genetic data from multigene testing can provide …
inherited prostate cancer (PCA). Clinical genetic data from multigene testing can provide …
[HTML][HTML] Role of genetic testing for inherited prostate cancer risk: Philadelphia Prostate Cancer Consensus Conference 2017
VN Giri, KE Knudsen, WK Kelly, W Abida… - Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
Purpose Guidelines are limited for genetic testing for prostate cancer (PCA). The goal of this
conference was to develop an expert consensus-driven working framework for …
conference was to develop an expert consensus-driven working framework for …
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