Genetic testing in prostate cancer management: Considerations informing primary care

VN Giri, TM Morgan, DS Morris… - CA: a cancer journal …, 2022 - Wiley Online Library
Inherited genetic mutations can significantly increase the risk for prostate cancer (PC), may
be associated with aggressive disease and poorer outcomes, and can have hereditary …

Germline testing and genetic counselling in prostate cancer

J Russo, VN Giri - Nature Reviews Urology, 2022 - nature.com
Genetic testing for prostate cancer is rapidly growing and is increasingly being driven by
precision medicine. Rates of germline pathogenic variants have been reported in up to 15 …

Practical considerations and challenges for germline genetic testing in patients with prostate cancer: recommendations from the germline genetics working group of …

BM Szymaniak, LA Facchini, VN Giri… - JCO oncology …, 2020 - ascopubs.org
Germline genetic testing is now routinely recommended for patients with prostate cancer
(PCa) because of expanded guidelines and options for targeted treatments. However …

Germline and somatic mutations in prostate cancer for the clinician

HH Cheng, AO Sokolova, EM Schaeffer… - Journal of the National …, 2019 - jnccn.org
It is increasingly important for clinicians involved in the management of prostate cancer to
understand the relevance of heritable (germline) mutations that, for select patients, affect …

Evolving intersection between inherited cancer genetics and therapeutic clinical trials in prostate cancer: a white paper from the Germline Genetics Working Group of …

MI Carlo, VN Giri, CJ Paller, W Abida… - JCO precision …, 2018 - ascopubs.org
Purpose Advances in germline genetics, and related therapeutic opportunities, present new
opportunities and challenges in prostate cancer. The Prostate Cancer Clinical Trials …

Germline genetic testing in advanced prostate cancer; practices and barriers: survey results from the Germline Genetics Working Group of the Prostate Cancer Clinical …

CJ Paller, ES Antonarakis, TM Beer, HT Borno… - Clinical genitourinary …, 2019 - Elsevier
Background Germline genetic testing increasingly identifies advanced prostate cancer
(PCa) patients who are candidates for precision therapies. The Prostate Cancer Clinical …

Barriers and facilitators of germline genetic evaluation for prostate cancer

S Loeb, R Li, T Sanchez Nolasco, N Byrne… - The …, 2021 - Wiley Online Library
Background Genetic counseling and germline testing have an increasingly important role for
patients with prostate cancer (PCa); however, recent data suggests they are underutilized …

Clinical implications of germline testing in newly diagnosed prostate cancer

S Loeb, VN Giri - European urology oncology, 2021 - Elsevier
Context Germline testing (GT) is increasingly impacting prostate cancer (PCa) management
and screening, with direct effects in urology, medical oncology, and radiation oncology. The …

Germline genetic testing for inherited prostate cancer in practice: Implications for genetic testing, precision therapy, and cascade testing

VN Giri, SE Hegarty, C Hyatt, E O'Leary, J Garcia… - The …, 2019 - Wiley Online Library
Background Genetic testing capability and guidelines are rapidly expanding to assess
inherited prostate cancer (PCA). Clinical genetic data from multigene testing can provide …

[HTML][HTML] Role of genetic testing for inherited prostate cancer risk: Philadelphia Prostate Cancer Consensus Conference 2017

VN Giri, KE Knudsen, WK Kelly, W Abida… - Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
Purpose Guidelines are limited for genetic testing for prostate cancer (PCA). The goal of this
conference was to develop an expert consensus-driven working framework for …