New look of EBV LMP1 signaling landscape
L Wang, S Ning - Cancers, 2021 - mdpi.com
Simple Summary Epstein-Barr Virus (EBV) infection is associated with various lymphomas
and carcinomas as well as other diseases in humans. The transmembrane protein LMP1 …
and carcinomas as well as other diseases in humans. The transmembrane protein LMP1 …
The Epstein–Barr virus LMP1 interactome: Biological implications and therapeutic targets
MR Cheerathodi, DG Meckes Jr - Future virology, 2018 - Taylor & Francis
The oncogenic potential of Epstein–Barr virus (EBV) is mostly attributed to latent membrane
protein 1 (LMP1), which is essential and sufficient for transformation of fibroblast and primary …
protein 1 (LMP1), which is essential and sufficient for transformation of fibroblast and primary …
NF-κB and IRF7 pathway activation by Epstein-Barr virus latent membrane protein 1
I Ersing, K Bernhardt, BE Gewurz - Viruses, 2013 - mdpi.com
The principal Epstein-Barr virus (EBV) oncoprotein, Latent Membrane Protein 1 (LMP1), is
expressed in most EBV-associated human malignancies. LMP1 mimics CD40 receptor …
expressed in most EBV-associated human malignancies. LMP1 mimics CD40 receptor …
Epstein-Barr virus LMP1-mediated oncogenicity
Epstein-Barr virus latent membrane protein 1 (LMP1) is expressed in multiple human
malignancies, including nasopharyngeal carcinoma and Hodgkin and immunosuppression …
malignancies, including nasopharyngeal carcinoma and Hodgkin and immunosuppression …
Evaluation of LMP1 of Epstein-Barr virus as a therapeutic target by its inhibition
A Hannigan, JB Wilson - Molecular cancer, 2010 - Springer
Background The latent membrane protein-1 (LMP1) encoded by Epstein-Barr virus (EBV) is
an oncoprotein which acts by constitutive activation of various signalling pathways, including …
an oncoprotein which acts by constitutive activation of various signalling pathways, including …
Viral oncoprotein LMP1 disrupts p53-induced cell cycle arrest and apoptosis through modulating K63-linked ubiquitination of p53
Disruption of the gatekeeper p53 tumor suppressor is involved in various virus-associated
tumorigeneses, with aberrant ubiquitination as the major cause of p53 abnormalities in virus …
tumorigeneses, with aberrant ubiquitination as the major cause of p53 abnormalities in virus …
[HTML][HTML] The interactome of EBV LMP1 evaluated by proximity-based BioID approach
MA Rider, MR Cheerathodi, SN Hurwitz, D Nkosi… - Virology, 2018 - Elsevier
Epstein-Barr virus LMP1 is an oncoprotein required for immortalizing B lymphocytes and
also plays important roles in transforming non-lymphoid tissue. The discovery of LMP1 …
also plays important roles in transforming non-lymphoid tissue. The discovery of LMP1 …
[HTML][HTML] An auto-regulatory loop for EBV LMP2A involves activation of Notch
LJ Anderson, R Longnecker - Virology, 2008 - Elsevier
LMP2A is consistently detected in Hodgkin's lymphoma, nasopharyngeal carcinoma and
has also been detected in Burkitt's lymphoma. Interestingly, LMP2A is detected in the …
has also been detected in Burkitt's lymphoma. Interestingly, LMP2A is detected in the …
[HTML][HTML] LIMD1 is induced by and required for LMP1 signaling, and protects EBV-transformed cells from DNA damage-induced cell death
L Wang, MEA Howell, B McPeak, K Riggs, C Kohne… - Oncotarget, 2018 - ncbi.nlm.nih.gov
LIMD1 (LIM domain-containing protein 1) is considered as a tumor suppressor, being
deregulated in many cancers to include hematological malignancies; however, very little is …
deregulated in many cancers to include hematological malignancies; however, very little is …
PRA1 promotes the intracellular trafficking and NF‐κB signaling of EBV latent membrane protein 1
Latent membrane protein 1 (LMP1), which is an Epstein–Barr virus (EBV)‐encoded
oncoprotein, induces nuclear factor‐kappa B (NF‐κB) signaling by mimicking the tumor …
oncoprotein, induces nuclear factor‐kappa B (NF‐κB) signaling by mimicking the tumor …