Background Osteoporosis poses a growing healthcare challenge owing to its rising
prevalence and a significant treatment gap, as patients are widely underdiagnosed and …

Some conditions are already known to be associated with an increased risk of osteoporotic
fractures. Other conditions may also be significant indicators of increased risk. The aim of the …

Background Prevention of osteoporotic fractures remains largely insufficient, and effective
means to identify patients at high, short-term fracture risk are needed. The FREM tool is …

We describe the collection of cohorts together with the analysis plan for an update of the
fracture risk prediction tool FRAX with respect to current and novel risk factors. The resource …

We aimed to develop and validate the FRActure Health Search (FRA-HS) score for
prediction of risk of osteoporotic fractures in primary care in Italy. We selected a cohort of …

Background Today, while there are effective drugs that reduce the risk of osteoporotic
fracture, yet there are no broadly accepted criteria that can be used to estimate risks and …

The objective of this study was to evaluate a Belgian version of the WHO fracture risk
assessment (FRAX) tool to compute 10-year probabilities of osteoporotic fracture in men and …

Background There is an ongoing discussion about incorporating additional risk factors to
established WHO fracture risk assessment tool (FRAX) to improve the prediction accuracy in …

Background In aging societies osteoporotic fractures are a major health problem with high
economic costs. Targeting prevention at individuals at high risk is important to reduce the …

A country-specific FRAX® model was developed from the epidemiology of fracture and
death in Belgium. Fracture probabilities were identified that corresponded to currently …