Why do probabilistic clinical models fail to transport between sites

TA Lasko, EV Strobl, WW Stead - npj Digital Medicine, 2024 - nature.com
The rising popularity of artificial intelligence in healthcare is highlighting the problem that a
computational model achieving super-human clinical performance at its training sites may …

Why Do Clinical Probabilistic Models Fail To Transport Between Sites?

TA Lasko, EV Strobl, WW Stead - arXiv preprint arXiv:2311.04787, 2023 - arxiv.org
The rising popularity of artificial intelligence in healthcare is highlighting the problem that a
computational model achieving super-human clinical performance at its training sites may …

Beyond performance metrics: modeling outcomes and cost for clinical machine learning

JA Diao, L Wedlund, J Kvedar - NPJ Digital Medicine, 2021 - nature.com
Advances in medical machine learning are expected to help personalize care, improve
outcomes, and reduce wasteful spending. In quantifying potential benefits, it is important to …

Learning in medicine: The importance of statistical thinking

M Russo, B Scarpa - Systems Medicine, 2022 - Springer
In many fields, including medicine and biology, there has been in the last years an
increasing diffusion and availability of complex data from different sources. Examples …

Real-world usage diminishes validity of Artificial Intelligence tools

A Vaid, A Sawant, M Suarez-Farinas, J Lee, S Kaul… - medRxiv, 2022 - medrxiv.org
Background Substantial effort has been directed towards demonstrating use cases of
Artificial Intelligence in healthcare, yet limited evidence exists about the long-term viability …

Improving the quality of machine learning in health applications and clinical research

BA Mateen, J Liley, AK Denniston, CC Holmes… - Nature Machine …, 2020 - nature.com
For machine learning developers, the use of prediction tools in real-world clinical settings
can be a distant goal. Recently published guidelines for reporting clinical research that …

Digital medicine and the curse of dimensionality

V Berisha, C Krantsevich, PR Hahn, S Hahn… - NPJ digital …, 2021 - nature.com
Digital health data are multimodal and high-dimensional. A patient's health state can be
characterized by a multitude of signals including medical imaging, clinical variables …

A giant with feet of clay: On the validity of the data that feed machine learning in medicine

F Cabitza, D Ciucci, R Rasoini - Organizing for the Digital World: IT for …, 2019 - Springer
This paper considers the use of machine learning in medicine by focusing on the main
problem that it has been aimed at solving or at least minimizing: uncertainty. However, we …

An operational guide to translational clinical machine learning in academic medical centers

M Poddar, JS Marwaha, W Yuan… - NPJ Digital …, 2024 - nature.com
Few published data science tools are ever translated from academia to real-world clinical
settings for which they were intended. One dimension of this problem is the software …

Computational approaches in precision medicine

J Espinal-Enríquez, RA Mejía-Pedroza… - … and Challenges in …, 2017 - Elsevier
To improve the performance of medical practice and the impact of biomedical research on
health treatment and policy making, a new way of looking at complex diseases is arising …