Alkaloids are heterocyclic bases with widespread occurrence in nature. Plants are rich and
easily accessible sources of them. Most isoquinoline alkaloids have cytotoxic activity for …

Alkaloids have protective functions for plants and can play an important role in living
organisms. Alkaloids may have a wide range of pharmacological activities. Many of them …

Background: Plants are an important origin of natural substances that the raw material for
various pharmaceutical and therapeutic applications due to the presence of phytochemicals …

Melanoma is a serious form of skin cancer that begins in cells known as melanocytes. While
it is less common than the other forms of skin cancer, melanoma is more dangerous …

The search for new substances with cytotoxic activity against various cancer cells, especially
cells that are very resistant to currently used chemotherapeutic agents, such as melanoma …

Quinolizidine alkaloids exhibit various forms of biological activity. A lot of them were found in
the Leguminosae family, including Laburnum and Genista. The aim of the study was the …

Melanoma is an enormous global health burden, and should be effectively addressed with
better therapeutic strategies. Therefore, new therapeutic agents are needed for the …

In the current study, 33 isoquinoline alkaloids belonging to protopine-, benzylisoquinoline-,
benzophenanthridine-, spirobenzylisoquinoline-, phthalideisoquinoline-, aporphine …

Abstract Context: Broussonetia papyrifera (L.) Vent.(Moraceae), a traditional Chinese
medicinal herb, has been extensively applied for many years to treat various diseases …

Isoquinoline alkaloids belong to the toxic secondary metabolites occurring in plants of many
families. The high biological activity makes these compounds promising agents for use in …