The formation of atherosclerotic plaques in the large and medium sized arteries is classically
driven by systemic factors, such as elevated cholesterol and blood pressure. However, work …

Atherosclerosis is a chronic, inflammatory disease of the arterial wall that underlies many of
the common causes of cardiovascular morbidity and mortality, including myocardial …

Atherosclerosis is the cause of death in more than 50% of people in Western societies. 21 In
addition, it results in significant cardiac morbidity, such as anginal syndromes, myocardial …

Most acute cardiovascular events are due to plaque rupture, with atheromas containing
large necrotic cores and thin fibrous caps being more susceptible to rupture and lesions with …

Atherosclerosis and associated ischemic organ dysfunction represent the number one
cause of mortality worldwide. While the key drivers of atherosclerosis, arterial hypertension …

There is abundant evidence that links hypercholesterolaemia to both vascular inflammation
and atherogenesis. While atherosclerosis is a large vessel disease that is characterized by …

Atherosclerosis is a complex disease process that affects very specific sites of the
vasculature. It is recognized that hemodynamic forces are largely responsible for dictating …

Phenotypic modulation of macrophages in response to plaque l... : Current Opinion in
Lipidology Phenotypic modulation of macrophages in response to plaque lipids : Current …

Atherosclerosis is a chronic inflammatory disease that arises from an imbalance in lipid
metabolism and a maladaptive immune response driven by the accumulation of cholesterol …

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of fatty
deposits in the inner walls of vessels. These plaques restrict blood flow and lead to …