[HTML][HTML] Complexes of Zn (II) with a mixed tryptanthrin derivative and curcumin chelating ligands as new promising anticancer agents
ZF Wang, QX Nong, HL Yu, QP Qin, FH Pan… - Dalton …, 2022 - pubs.rsc.org
In this study, two novel curcumin (H-Cur)–tryptanthrin metal compounds—[Zn (TA) Cl2], ie,
Zn (TA), and [Zn (TA)(Cur)] Cl, ie, Zn (TAC)—were synthesized and investigated using 5-(bis …
Zn (TA), and [Zn (TA)(Cur)] Cl, ie, Zn (TAC)—were synthesized and investigated using 5-(bis …
[HTML][HTML] Tryptanthrin derivative copper (II) complexes with high antitumor activity by inhibiting telomerase activity, and inducing mitochondria-mediated apoptosis and …
QP Qin, BQ Zou, MX Tan, SL Wang, YC Liu… - New Journal of …, 2018 - pubs.rsc.org
The copper (II) complexes of tryptanthrin (Try) and 8-bromo-tryptanthrin (BrTry),[CuII (Try)
2Cl2](Try-Cu) and [CuII (BrTry) 2Cl2](BrTry-Cu), were synthesized and fully characterized by …
2Cl2](Try-Cu) and [CuII (BrTry) 2Cl2](BrTry-Cu), were synthesized and fully characterized by …
Structure elucidation, in vitro binding studies and ROS-dependent anti-cancer activity of Cu(II) and Zn(II) phthaloylglycinate(phen) complexes against MDA-MB-231 …
S Zehra, I Cirilli, S Silvestri, S Gómez-Ruiz… - Metallomics, 2021 - academic.oup.com
New mononuclear Cu (II) and Zn (II)-based complexes 1 [Cu (L) 2 (diimine) HOCH3] and 2
[Zn (L) 2 (diimine)] have been synthesized as anti-cancer chemotherapeutics targeted to …
[Zn (L) 2 (diimine)] have been synthesized as anti-cancer chemotherapeutics targeted to …
Ferrocene conjugated copper (II) complexes of terpyridine and traditional Chinese medicine (TCM) anticancer ligands showing selective toxicity towards cancer cells
B Deka, A Bhattacharyya, S Mukherjee… - Applied …, 2018 - Wiley Online Library
Six novel mixed‐ligand copper (II) complexes, namely,[Cu (R‐tpy)(L)] NO3 (1–6), where R‐
tpy is 4′‐phenyl‐2, 2′: 6′, 2′′‐terpyridine (Ph‐tpy; 1–3) and 4′‐ferrocenyl‐2, 2 …
tpy is 4′‐phenyl‐2, 2′: 6′, 2′′‐terpyridine (Ph‐tpy; 1–3) and 4′‐ferrocenyl‐2, 2 …
[HTML][HTML] In vitro and in vivo anticancer activity of a thiourea tripyridyl dinuclear Cu (ii) complex
J Jin, J Hu, Y Qin, J Zhang, L Yue, H Hou - New Journal of Chemistry, 2019 - pubs.rsc.org
Metal-based anticancer drugs have been gaining attention recently. In this study we
identified and characterized a dinuclear complex,[Cu2 (dppc) 2I2](1)(dppc= 2-(di (pyridin-2 …
identified and characterized a dinuclear complex,[Cu2 (dppc) 2I2](1)(dppc= 2-(di (pyridin-2 …
[HTML][HTML] Terpyridine copper (II) complexes as potential anticancer agents by inhibiting cell proliferation, blocking the cell cycle and inducing apoptosis in BEL-7402 …
YQ Gu, YJ Zhong, MQ Hu, HQ Li, K Yang, Q Dong… - Dalton …, 2022 - pubs.rsc.org
Four mononuclear terpyridine complexes [Cu (H-La) Cl2]· CH3OH (1),[Cu (H-La) Cl] ClO4
(2),[Cu (H-Lb) Cl2]· CH3OH (3), and [Cu (H-Lb)(CH3OH)(DMSO)](ClO4) 2 (4) were prepared …
(2),[Cu (H-Lb) Cl2]· CH3OH (3), and [Cu (H-Lb)(CH3OH)(DMSO)](ClO4) 2 (4) were prepared …
Novel zinc (II)− curcumin molecular probes bearing berberine and jatrorrhizine derivatives as potential mitochondria-targeting anti-neoplastic drugs
SH Zhang, ZF Wang, H Tan - European Journal of Medicinal Chemistry, 2022 - Elsevier
Berberine and jatrorrhizine are major bioactive components that are emerging as potential
anti-cancer drugs. However, no zinc (II)–berberine/jatrorrhizine–curcumin compounds have …
anti-cancer drugs. However, no zinc (II)–berberine/jatrorrhizine–curcumin compounds have …
Mechanistic insights into a novel chromone-appended Cu (II) anticancer drug entity: in vitro binding profile with DNA/RNA substrates and cytotoxic activity against …
I Yousuf, F Arjmand, S Tabassum, L Toupet… - Dalton …, 2015 - pubs.rsc.org
A new chromone-appended Cu (II) drug entity (1) was designed and synthesized as a
potential anticancer chemotherapeutic agent. The structural elucidation was carried out …
potential anticancer chemotherapeutic agent. The structural elucidation was carried out …
Mitochondria-localizing curcumin-cryptolepine Zn (II) complexes and their antitumor activity
LQ Qin, CJ Liang, Z Zhou, QP Qin, ZZ Wei… - Bioorganic & Medicinal …, 2021 - Elsevier
Many metal complexes are potent candidates as mitochondrial-targeting agents. In this
study, four novel Zn (II) complexes,[Zn (BPQA) Cl 2](Zn1),[Zn (BPQA)(Curc)] Cl (Zn2),[Zn …
study, four novel Zn (II) complexes,[Zn (BPQA) Cl 2](Zn1),[Zn (BPQA)(Curc)] Cl (Zn2),[Zn …
Improving the bioactivity of Zn (II)-curcumin based complexes
D Pucci, A Crispini, BS Mendiguchía, S Pirillo… - Dalton …, 2013 - pubs.rsc.org
New Zn (II)-curcumin based heteroleptic complexes (1–5) have been synthesized and fully
characterized, with the aim to improve the bioactivity of the precursor derivative [(bpy-9) Zn …
characterized, with the aim to improve the bioactivity of the precursor derivative [(bpy-9) Zn …