Protecting the vulnerable: addressing the COVID-19 care needs of people with compromised immunity

RR Razonable - Frontiers in immunology, 2024 - frontiersin.org
While the general population regained a certain level of normalcy with the end of the global
health emergency, the risk of contracting COVID-19 with a severe outcome is still a major …

The burden of COVID-19 in the immunocompromised patient: implications for vaccination and needs for the future

A Antinori, M Bausch-Jurken - The Journal of Infectious …, 2023 - academic.oup.com
Approximately 3% of US adults are immunocompromised and less capable of fighting
infections such as SARS-CoV-2 (the causative agent of COVID-19). Individuals may be …

[HTML][HTML] Vaccines and therapeutics for immunocompromised patients with COVID-19

S Shoham, C Batista, YB Amor, O Ergonul… - …, 2023 - thelancet.com
The COVID-19 pandemic has disproportionately impacted immunocompromised patients.
This diverse group is at increased risk for impaired vaccine responses, progression to …

Immunocompromised individuals are at increased risk of COVID‐19 breakthrough infection, hospitalization, and death in the post‐vaccination era: A systematic review

J Bytyci, Y Ying, LYW Lee - Immunity, Inflammation and …, 2024 - Wiley Online Library
Introduction Immunocompromised individuals have been shown to mount a reduced
response to vaccination, resulting in reduced vaccine effectiveness in this cohort. Therefore …

Immunocompromised patients and COVID-19: how do we protect those most at risk?

J Schneider, J Erber, L Renders… - Expert Review of Anti …, 2024 - Taylor & Francis
Population immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has increased during the pandemic because of vaccination campaigns and …

Clinical course and management of COVID-19 in the era of widespread population immunity

EA Meyerowitz, J Scott, A Richterman, V Male… - Nature Reviews …, 2024 - nature.com
The clinical implications of COVID-19 have changed since SARS-CoV-2 first emerged in
humans. The current high levels of population immunity, due to prior infection and/or …

Immunogenicity of COVID-19 vaccination in immunocompromised patients: an observational, prospective cohort study interim analysis

G Haidar, M Agha, A Lukanski, K Linstrum, R Troyan… - MedRxiv, 2021 - medrxiv.org
Objectives Immunocompromised patients were excluded from COVID-19 vaccine clinical
trials. The objectives of the study were to measure antibody responses, levels, and …

[HTML][HTML] Brief research report: impact of vaccination on antibody responses and mortality from severe COVID-19

B Adhikari, JS Bednash, JC Horowitz… - Frontiers in …, 2024 - frontiersin.org
Introduction While it is established that vaccination reduces risk of hospitalization, there is
conflicting data on whether it improves outcome among hospitalized COVID-19 patients …

[HTML][HTML] Coronavirus disease 2019 (COVID-19) crisis: losing our immunity when we need it the most

A Ghanemi, M Yoshioka, J St-Amand - Biology, 2021 - mdpi.com
Simple Summary With the current coronavirus disease 2019 (COVID-19) crisis, humans
have developed new habits and adapted to a novel socioeconomic reality. Indeed …

[HTML][HTML] The COVID-19 pandemic threatens the Expanded Program on Immunization: recommendations for sustaining vaccination goals

H Hamid, TH Mallhi, MS Naseer, I Younas… - Drugs & Therapy …, 2020 - Springer
Background Spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2;
COVID-19) pandemic has been unprecedented and affected daily activities at all levels …