[HTML][HTML] Biology and therapeutic targets of colorectal serrated adenocarcinoma; clues for a histologically based treatment against an aggressive tumor
B Alburquerque-González, FF López-Calderón… - International Journal of …, 2020 - mdpi.com
Serrated adenocarcinoma (SAC) is a tumor recognized by the WHO as a histological
subtype accounting for around 9% of colorectal carcinomas. Compared to conventional …
subtype accounting for around 9% of colorectal carcinomas. Compared to conventional …
Expression profiling shows differential molecular pathways and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma
P Conesa‐Zamora, J García‐Solano… - … journal of cancer, 2013 - Wiley Online Library
Serrated adenocarcinoma (SAC) is a recently recognized colorectal cancer (CRC) subtype
accounting for 7.5 to 8.7% of CRCs. It has been shown that SAC has a poorer prognosis and …
accounting for 7.5 to 8.7% of CRCs. It has been shown that SAC has a poorer prognosis and …
Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis
P Laiho, A Kokko, S Vanharanta, R Salovaara… - Oncogene, 2007 - nature.com
Serrated colorectal carcinomas (CRCs) are morphologically different from conventional
CRCs and have been proposed to follow a distinct pathway of CRC formation. Despite …
CRCs and have been proposed to follow a distinct pathway of CRC formation. Despite …
[HTML][HTML] Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes
D Hirano, Y Urabe, S Tanaka, K Nakamura… - Plos one, 2019 - journals.plos.org
Serrated adenocarcinoma (SAC) is considered the end stage of the serrated neoplasia
pathway. Although SAC prognosis is not widely recognized, the serrated pathway …
pathway. Although SAC prognosis is not widely recognized, the serrated pathway …
[HTML][HTML] Serrated pathway adenocarcinomas: molecular and immunohistochemical insights into their recognition
S Gurzu, Z Szentirmay, E Toth, T Bara, T Bara Jr… - PLoS …, 2013 - journals.plos.org
Introduction Colorectal adenocarcinomas (CRC) developed through serrated pathway seem
to present particular behavior compared with the non-serrated ones, but recognition of them …
to present particular behavior compared with the non-serrated ones, but recognition of them …
Clinical, pathological genetics and intratumoral immune milieu of serrated adenocarcinoma of the colon
Background Serrated adenocarcinoma (SAC), a recognised WHO variant of colonic
adenocarcinoma, is the purported end‐product of serrated neoplasia. However, the …
adenocarcinoma, is the purported end‐product of serrated neoplasia. However, the …
VE1 immunohistochemistry accurately detects BRAF V600E mutations in colorectal carcinoma and can be utilized in the detection of poorly differentiated colorectal …
S Sajanti, P Sirniö, JP Väyrynen, A Tuomisto, K Klintrup… - Virchows Archiv, 2014 - Springer
Serrated adenocarcinoma (SAC) is a recently defined subtype of colorectal carcinoma
(CRC). However, in cases where an adjacent serrated adenoma is absent and the …
(CRC). However, in cases where an adjacent serrated adenoma is absent and the …
[HTML][HTML] Serrated colorectal cancer: Preclinical models and molecular pathways
A Aiderus, N Barker, V Tergaonkar - Trends in Cancer, 2023 - cell.com
Serrated lesions are histologically heterogeneous, and detection can be challenging as
these lesions have subtle features that may be missed by endoscopy. Furthermore, while …
these lesions have subtle features that may be missed by endoscopy. Furthermore, while …
Serrated colorectal cancer: the road less travelled?
Y Nakanishi, MT Diaz-Meco, J Moscat - Trends in cancer, 2019 - cell.com
Studies of colorectal cancer (CRC) originating through the conventional adenoma-
carcinoma sequence have provided insight into the molecular mechanisms controlling its …
carcinoma sequence have provided insight into the molecular mechanisms controlling its …
[HTML][HTML] Molecular features of the serrated pathway to colorectal cancer: current knowledge and future directions
C Satorres, M García-Campos… - Gut and Liver, 2021 - ncbi.nlm.nih.gov
Serrated lesions are the precursor lesions of a new model of colorectal carcinogenesis.
From a molecular standpoint, the serrated pathway is thought to be responsible for up to …
From a molecular standpoint, the serrated pathway is thought to be responsible for up to …