Serrated adenocarcinoma (SAC) is a tumor recognized by the WHO as a histological
subtype accounting for around 9% of colorectal carcinomas. Compared to conventional …

Serrated adenocarcinoma (SAC) is a recently recognized colorectal cancer (CRC) subtype
accounting for 7.5 to 8.7% of CRCs. It has been shown that SAC has a poorer prognosis and …

Serrated colorectal carcinomas (CRCs) are morphologically different from conventional
CRCs and have been proposed to follow a distinct pathway of CRC formation. Despite …

Serrated adenocarcinoma (SAC) is considered the end stage of the serrated neoplasia
pathway. Although SAC prognosis is not widely recognized, the serrated pathway …

Introduction Colorectal adenocarcinomas (CRC) developed through serrated pathway seem
to present particular behavior compared with the non-serrated ones, but recognition of them …

Background Serrated adenocarcinoma (SAC), a recognised WHO variant of colonic
adenocarcinoma, is the purported end‐product of serrated neoplasia. However, the …

Serrated adenocarcinoma (SAC) is a recently defined subtype of colorectal carcinoma
(CRC). However, in cases where an adjacent serrated adenoma is absent and the …

Serrated lesions are histologically heterogeneous, and detection can be challenging as
these lesions have subtle features that may be missed by endoscopy. Furthermore, while …

Studies of colorectal cancer (CRC) originating through the conventional adenoma-
carcinoma sequence have provided insight into the molecular mechanisms controlling its …

Serrated lesions are the precursor lesions of a new model of colorectal carcinogenesis.
From a molecular standpoint, the serrated pathway is thought to be responsible for up to …