Identifying sex differences in outcomes and toxicity between males and females in oncology
clinical trials is important and has also been mandated by National Institutes of Health …

Many aspects of human health and disease are influenced by sex as a biological variable
and gender as a social construct. A recent study from Nature Communications reported the …

Sex is an essential biological variable that influences the development, progression and
response to treatment in cancer. Despite this, early-phase cancer clinical trials frequently …

Background The objective of this study was to evaluate whether sex-and gender-based
analyses and proper sex and gender terminology were used in oncology trials leading to …

Important differences in cancer risk and survival between male and female patients have
been documented in the past few decades, with the latter having a reduced risk and better …

The prevalence, incidence, and severity of a wide variety of diseases and ailments are
significantly influenced by the significant disparities that occur between the sexes. The way …

Despite the compelling evidence for greater toxicity in female patients, sex-specific
anticancer treatment strategies are missing. Increased awareness of sex differences at all …

The study population within phase III clinical trials leading to approval of new cancer agents
should ideally more closely mirror the population who will ultimately receive these agents …

Thus we ignore what we don't know. In oncology, it is traditionally assumed that men and
women are equal. As a result, sex differences in treatment effects and the biology of non-sex …

Curing cancer through precision medicine is the paramount aim of the new wave of
molecular and genomic therapies. Currently, whether patients with non-reproductive …