UbiNAAT: a multiplexed point-of-care nucleic acid diagnostic platform for rapid at-home pathogen detection

KP Jiang, S Bennett, EK Heiniger, S Kumar, P Yager - Lab on a Chip, 2024 - pubs.rsc.org
The COVID-19 pandemic increased demands for respiratory disease testing to facilitate
treatment and limit transmission, demonstrating in the process that most existing test options …

Promise and perils of paper-based point-of-care nucleic acid detection for endemic and pandemic pathogens

N Sritong, MS de Medeiros, LA Basing, JC Linnes - Lab on a Chip, 2023 - pubs.rsc.org
From HIV and influenza to emerging pathogens like COVID-19, each new infectious disease
outbreak has highlighted the need for massively-scalable testing that can be performed …

A sample-to-answer, portable platform for rapid detection of pathogens with a smartphone interface

YD Ma, KH Li, YH Chen, YM Lee, ST Chou, YY Lai… - Lab on a Chip, 2019 - pubs.rsc.org
Emerging and re-emerging infectious diseases pose global threats to human health.
Although several conventional diagnostic methods have been widely adopted in the clinic …

Development of a self-contained microfluidic chip and an internet-of-things-based point-of-care device for automated identification of respiratory viruses

HQ Nguyen, VD Nguyen, VM Phan, TS Seo - Lab on a Chip, 2024 - pubs.rsc.org
The COVID-19 pandemic greatly impacted the in vitro diagnostic market, leading to the
development of new technologies such as point-of-care testing (POCT), multiplex testing …

Development and initial results of a low cost, disposable, point-of-care testing device for pathogen detection

JP Bearinger, LC Dugan, BR Baker… - IEEE transactions on …, 2010 - ieeexplore.ieee.org
Development of small footprint, disposable, fast, and inexpensive devices for pathogen
detection in the field and clinic would benefit human and veterinary medicine by allowing …

Smart cup: a minimally-instrumented, smartphone-based point-of-care molecular diagnostic device

SC Liao, J Peng, MG Mauk, S Awasthi, J Song… - Sensors and Actuators B …, 2016 - Elsevier
Nucleic acid amplification-based diagnostics offer rapid, sensitive, and specific means for
detecting and monitoring the progression of infectious diseases. However, this method …

Point-of-care molecular diagnostic systems—past, present and future

CA Holland, FL Kiechle - Current opinion in microbiology, 2005 - Elsevier
The field of molecular diagnostics has greatly decreased the time it takes to identify
infectious agents and to test their antimicrobial resistance. Portable devices are currently in …

A handheld point-of-care genomic diagnostic system

FB Myers, RH Henrikson, J Bone, LP Lee - PloS one, 2013 - journals.plos.org
The rapid detection and identification of infectious disease pathogens is a critical need for
healthcare in both developed and developing countries. As we gain more insight into the …

A pocket-sized device automates multiplexed point-of-care RNA testing for rapid screening of infectious pathogens

B Shu, L Lin, B Wu, E Huang, Y Wang, Z Li, H He… - Biosensors and …, 2021 - Elsevier
Rapid screening of infectious pathogens at the point-of-care (POC) is ideally low-cost,
portable, easy to use, and capable of multiplex detection with high sensitivity. However …

Integrated, automated, fast PCR system for point-of-care molecular diagnosis of bacterial infection

D Lee, D Kim, J Han, J Yun, KH Lee, GM Kim, O Kwon… - Sensors, 2021 - mdpi.com
We developed an integrated PCR system that performs automated sample preparation and
fast polymerase chain reaction (PCR) for application in point-of care (POC) testing. This …