Highlights in antiviral drug research: antivirals at the horizon

ED Clercq - Medicinal Research Reviews, 2013 - Wiley Online Library
This review highlights ten “hot topics” in current antiviral research:(i) new nucleoside
derivatives (ie, PSI‐352938) showing high potential as a direct antiviral against hepatitis C …

Another ten stories in antiviral drug discovery (part C):“old” and “new” antivirals, strategies, and perspectives

E De Clercq - Medicinal research reviews, 2009 - Wiley Online Library
The ten stories told here deal with (i) ribavirin as an inhibitor of IMP dehydrogenase and (ii)
ribavirin, in combination with pegylated interferon, as the present “standard of care” for …

The next ten stories on antiviral drug discovery (part E): advents, advances, and adventures

E De Clercq - Medicinal research reviews, 2011 - Wiley Online Library
This review article presents the fifth part (part E) in the series of stories on antiviral drug
discovery. The ten stories belonging to this fifth part are dealing with (i) aurintricarboxylic …

Antiviral drug discovery: ten more compounds, and ten more stories (part B)

E De Clercq - Medicinal Research Reviews, 2009 - Wiley Online Library
This review article that complements the previous review article on “The discovery of
antiviral agents: ten different compounds, ten different stories” presents ten more …

Yet another ten stories on antiviral drug discovery (part D): paradigms, paradoxes, and paraductions

E De Clercq - Medicinal Research Reviews, 2010 - Wiley Online Library
This review article presents the fourth part (part D) in the series of stories on antiviral drug
discovery. The stories told in part D focus on:(i) the cyclotriazadisulfonamide compounds;(ii) …

[HTML][HTML] Three decades of antiviral drugs

ED Clercq - Nature Reviews Drug Discovery, 2007 - nature.com
Three decades of antiviral drugs | Nature Reviews Drug Discovery Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

[HTML][HTML] Innovation and trends in the development and approval of antiviral medicines: 1987–2017 and beyond

S Chaudhuri, JA Symons, J Deval - Antiviral research, 2018 - Elsevier
Abstract 2017 marked the 30th anniversary of the approval of zidovudine (AZT) as the first
HIV/AIDS therapy. Since then, more than eighty antiviral drugs have received FDA approval …

Antiviral drug discovery and development: where chemistry meets with biomedicine

E De Clercq - Antiviral research, 2005 - Elsevier
The successful development of antiviral drugs is highly dependent on a close interaction
and collaboration between the chemist and the biologist (biomedic). This is illustrated by a …

[HTML][HTML] An Odyssey in antiviral drug development—50 years at the Rega Institute: 1964–2014

E De Clercq - Acta Pharmaceutica Sinica. B, 2015 - ncbi.nlm.nih.gov
I entered the Rega Institute for Medical Research in August 1964, as a medical student, to
start working under the guidance of Prof. Piet De Somer, then professor of microbiology at …

Antivirals become a broader enterprise

JL Fox - Nature Biotechnology, 2007 - nature.com
Antivirals become a broader enterprise | Nature Biotechnology Skip to main content Thank you
for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …