At the outset of solid organ transplantation, genetic variation between donors and recipients
was recognized as a major player in mechanisms such as allograft tolerance and rejection …

Genetic compatibilities between donor and recipient represent an important determinant of
rejection and long-term allograft survival. Genetic background of transplant donors may be …

Background. Genetic association studies of transplantation outcomes have been hampered
by small samples and highly complex multifactorial phenotypes, hindering investigations of …

Over the last decade, advances in genetic technologies have accelerated our understanding
of the genetic diversity across individuals and populations. Case–control and population …

An extensive body of research about team science provides empirical evidence that diverse
teams outperform homogenous teams in creating more innovative solutions to complex …

Renal transplantation has transformed the life of patients with end-stage renal disease and
other chronic kidney disorders by returning endogenous kidney function and enabling …

Ever since the discovery of the major histocompatibility complex, scientific and clinical
understanding in the field of transplantation has been advanced through genetic and …

Over the last decade, the search for gene variants with the potential to influence transplant
outcomes or predispose individuals to host–recipient-related phenotypes has generated a …

In the era of whole genome sequencing, genome-wide association studies, mainly using
single nucleotide polymorphisms (SNPs), have allowed the identification of novel genes or …

Kidney transplantation has become the preferred method of renal replacement. However,
the rate of long term allograft survival has not changed over the last decade. Donor and …