RISUG® as a male contraceptive: journey from bench to bedside

B Khilwani, A Badar, AS Ansari, NK Lohiya - Basic and Clinical Andrology, 2020 - Springer
Even after decades of research men still lack reliable and reversible contraceptive methods
comparable to female methods of contraception. Traditional methods of male contraception …

RISUG: An intravasal injectable male contraceptive

NK Lohiya, I Alam, M Hussain, SR Khan… - Indian Journal of …, 2014 - journals.lww.com
Over the last two decades RISUG has been drawing attention in the field of male
contraception. It promises to sterile men for a period of up to 10-15 years. According to …

Safety & efficacy of an intravasal, one-time injectable & non-hormonal male contraceptive (RISUG): A clinical experience

RS Sharma, AK Mathur, R Singh, HC Das… - Indian Journal of …, 2019 - journals.lww.com
Methods: One hundred and thirty nine young males each having at least two children and
living with wife were given 120 μl of RISUG as bilateral vas intraluminal injection. After the …

Phase II clinical trial of a vas deferens injectable contraceptive for the male

SK Guha, G Singh, S Ansari, S Kumar, A Srivastava… - Contraception, 1997 - Elsevier
Following up on an earlier clinical trial demonstrating the safety of an intra-vas deferens
injection of a contraceptive drug named Risug, comprised of styrene maleic anhydride …

RISUG™(reversible inhibition of sperm under guidance)–an antimicrobial as male vas deferens implant for HIV free semen

SK Guha - Medical hypotheses, 2005 - Elsevier
HIV transmission from the male to the female is a major health problem. A hypothesis
proposing an intra vas deferens implant of an antimicrobial compound to prevent the …

A short-term evaluation of semen and accessory sex gland function in phase III trial subjects receiving intravasal contraceptive RISUG

SP Chaki, HC Das, MM Misro - Contraception, 2003 - Elsevier
Following the intravasal injection of a new male contraceptive RISUG (reversible inhibition
of sperm under guidance) in volunteers, routine semen analysis, semen biochemistry and …

[HTML][HTML] The future of male contraception: a fertile ground

I Khourdaji, J Zillioux, K Eisenfrats… - … andrology and urology, 2018 - ncbi.nlm.nih.gov
The continued and rapid expansion of the Earth's population mandates the need for safe
and effective measures of contraception. While a plethora of options exist for women …

[PDF][PDF] A proton NMR study of the effect of a new intravasal injectable male contraceptive RISUG on seminal plasma metabolites

U Sharma, K Chaudhury, NR Jagannathan… - REPRODUCTION …, 2001 - academia.edu
There is a need to develop a suitable male contraceptive for population control programmes.
The current unavailability of an ideal male contraceptive is due to the lack of one or more …

Two-year clinical efficacy trial with dose variations of a vas deferens injectable contraceptive for the male

SK Guha, G Singh, A Srivastava, HC Das, JC Bhardwaj… - Contraception, 1998 - Elsevier
Contraceptive action of a single intra–vas deferens injection of a specific preparation of
styrene maleic anhydride (SMA) dissolved in dimethyl sulphoxide, forming a drug given the …

[HTML][HTML] Emerging approaches to male contraception

A Thirumalai, JK Amory - Fertility and sterility, 2021 - Elsevier
Despite significant interests in contraception by men, effective methods of male
contraception are limited to vasectomy and condoms. Recently, there have been several …