Osteoporosis, one of the serious health diseases, involves bone mass loss, bone density
diminishing, and degeneration of bone microstructure, which is accompanied by a tendency …

Wnt is a major signaling pathway involved in multifaceted roles of various biological
processes. Bones are dynamic tissues which are able to remodel and maintain the tissue …

The Wnt signaling pathway plays an important role not only in embryonic development but
also in the maintenance and differentiation of the stem cells in adulthood. In particular, Wnt …

Wnt signaling executes an indispensable performance in osteoblast differentiation, bone
development, homeostasis, and remodeling. Wnt signals trigger the intracellular Wnt …

Wnt, a secreted glycoprotein, has an approximate molecular weight of 40 kDa, and it is a
cytokine involved in various biological phenomena including ontogeny, morphogenesis …

The Wnt signalling pathway is one of the central signalling pathways in bone development,
homeostasis and regulation of bone mineral density. It consists of numerous Wnt ligands …

Wnt signaling affects both bone modeling, which occurs during development, and bone
remodeling, which is a lifelong process involving tissue renewal. Wnt signals are especially …

The prevention and treatment of osteoporosis traditionally involves the use of antiresorptive
agents that target osteoclast function. Antiresorptive therapy is not associated with a …

Wnt signalling has an essential role in regulating bone formation and remodelling during
embryonic development and throughout postnatal and adult life. Specifically, Wnt signalling …

Abstract Objectives The Wnt signaling pathway is a key pathway in various processes,
including bone metabolism. In this review, current knowledge of all extracellular modulators …