New and evolving concepts in the neurotoxicology of lead
LD White, DA Cory-Slechta, ME Gilbert… - Toxicology and applied …, 2007 - Elsevier
Lead (Pb) is a xenobiotic metal with no known essential function in cellular growth,
proliferation, or signaling. Decades of research characterizing the toxicology of Pb have …
proliferation, or signaling. Decades of research characterizing the toxicology of Pb have …
Childhood lead exposure and adult neurodegenerative disease
A Reuben - Journal of Alzheimer's Disease, 2018 - content.iospress.com
Millions of Americans now entering midlife and old age were exposed to high levels of lead,
a neurotoxin, as children. Evidence from animal-model and human observational studies …
a neurotoxin, as children. Evidence from animal-model and human observational studies …
Neurotoxicity of low-level lead exposure: History, mechanisms of action, and behavioral effects in humans and preclinical models
A Rocha, KA Trujillo - Neurotoxicology, 2019 - Elsevier
Lead is a neurotoxin that produces long-term, perhaps irreversible, effects on health and
well-being. This article summarizes clinical and preclinical studies that have employed a …
well-being. This article summarizes clinical and preclinical studies that have employed a …
Molecular mechanisms of lead neurotoxicity
MB Virgolini, M Aschner - Advances in neurotoxicology, 2021 - Elsevier
Abstract Lead (Pb 2+) is a non-essential metal with numerous industrial applications that
have led to its ubiquity in the environment. Thus, not only occupational-exposed individuals' …
have led to its ubiquity in the environment. Thus, not only occupational-exposed individuals' …
[HTML][HTML] Cognitive impairment induced by lead exposure during lifespan: mechanisms of lead neurotoxicity
DR Ortega, DFG Esquivel, TB Ayala, B Pineda… - Toxics, 2021 - ncbi.nlm.nih.gov
Lead (Pb) is considered a strong environmental toxin with human health repercussions. Due
to its widespread use and the number of people potentially exposed to different sources of …
to its widespread use and the number of people potentially exposed to different sources of …
[HTML][HTML] Cognitive Impairment Induced by lead exposure during Lifespan: mechanisms of lead neurotoxicity
D Ramírez Ortega, DF González Esquivel… - Toxics, 2021 - mdpi.com
Lead (Pb) is considered a strong environmental toxin with human health repercussions. Due
to its widespread use and the number of people potentially exposed to different sources of …
to its widespread use and the number of people potentially exposed to different sources of …
Lead-induced endoplasmic reticulum (ER) stress responses in the nervous system
Y Qian, E Tiffany-Castiglioni - Neurochemical research, 2003 - Springer
Lead (Pb) poisoning continues to be a significant health risk because of its pervasiveness in
the environment, its known neurotoxic effects in children, and potential endogenous …
the environment, its known neurotoxic effects in children, and potential endogenous …
Zebrafish as a model for investigating developmental lead (Pb) neurotoxicity as a risk factor in adult neurodegenerative disease: a mini-review
J Lee, JL Freeman - Neurotoxicology, 2014 - Elsevier
Lead (Pb) exposure has long been recognized to cause neurological alterations in both
adults and children. While most of the studies in adults are related to higher dose exposure …
adults and children. While most of the studies in adults are related to higher dose exposure …
Developmental neurotoxicity of lead
S Caito, M Aschner - Neurotoxicity of metals, 2017 - Springer
Lead exposure is a major concern for the developing nervous system. Environmental
exposures to lead, predominantly from contaminated water or lead paint chips, account for …
exposures to lead, predominantly from contaminated water or lead paint chips, account for …
Molecular targets of lead in brain neurotoxicity
C Marchetti - Neurotoxicity research, 2003 - Springer
The detrimental effects of lead poisoning have been well known since ancient times, but
some of the most severe consequences of exposure to this metal have only been described …
some of the most severe consequences of exposure to this metal have only been described …