During nervous system development, neurons extend axons to reach their targets and form
functional circuits. The faulty assembly or disintegration of such circuits results in disorders …

As the nervous system develops, newly differentiated neurons need to extend their axons
toward their synaptic targets to form functional neural circuits. During this highly dynamic …

Axons need to be properly guided to their targets to form synaptic connections, and this
requires interactions between highly conserved extracellular and transmembrane ligands …

The development of precise connectivity patterns during the establishment of the nervous
system depends on the regulated action of diverse, conserved families of guidance cues …

Axons follow highly stereotyped and reproducible trajectories to their targets. In this review
we address the properties of the first pioneer neurons to grow in the developing nervous …

The complex patterns of neuronal wiring in the adult nervous system depend on a series of
guidance events during neural development that establish a framework on which functional …

▪ Abstract The guidance of axons during the establishment of the nervous system is
mediated by a variety of extracellular cues that govern cytoskeletal dynamics in axonal …

In order to form a functional nervous system, neurones extend axons, often over long
distances, to reach their targets. This process is controlled by extracellular receptors and …

The normal function of the nervous system requires that the constituent neurons are
preciselywired together'. During embryogenesis, each neuron extends an axonal process …

The guidance of axons to their targets represents a key stage in the assembly of the nervous
system, linking the early inductive interactions that establish neuronal identity to the later …