Quantitative autoradiography of angiotensin II receptors in the SHR brain

DR Gehlert, RC Speth, JK Wamsley - Peptides, 1986 - Elsevier
Several lines of evidence indicate brain angiotensin II is associated with the elevation of
blood pressure seen in the spontaneously hypertensive rat (SHR). These include an …

Angiotensin-like immunoreactivity in the brain of the spontaneously hypertensive rat.

JA Weyhenmeyer, MI Phillips - Hypertension, 1982 - Am Heart Assoc
Evidence for the brain renin-angiotensin system being involved in the hypertension of the
spontaneously hypertensive rat (SHR) includes central administration of angiotensin II (AII) …

Autoradiographic localization of angiotensin II receptors in the rat brainstem

DR Gehlert, RC Speth, DP Healy, JK Wamsley - Life sciences, 1984 - Elsevier
The microscopic localization of angiotensin II receptors in the rat brainstem has been
accomplished utilizing in vitro receptor autoradiographic techniques. These receptors are …

Brain angiotensin II and III binding and dipsogenicity in the rabbit

JW Wright, MJ Sullivan, EP Petersen, JW Harding - Brain research, 1985 - Elsevier
The rabbit brain evidence low or non-detectable levels of [125 I] angiotensin II binding but
considerable [125 I] angiotensin III specific binding in agreement with distributions reported …

Angiotensin II in rat brain comigrates with authentic angiotensin II in high pressure liquid chromatography.

MI Phillips, B Stenstrom - Circulation research, 1985 - Am Heart Assoc
Indirect evidence has implicated a role for central angiotensin II in blood pressure control. To
answer directly the question of whether angiotensin II exists in the brain, independent of …

Autoradiographic localization of angiotensin receptors in the sheep brain

MJ McKinley, A Allen, J Clevers, DA Denton… - Brain research, 1986 - Elsevier
Abstract Binding of [125 I]-(Sar 1, Ile 8) angiotensin II (AII) to frozen sections of sheep brain
was determined by in vitro autoradiography. Greatest AII-binding occurred in the organum …

Distribution of [125I] angiotensin II binding sites in the rat brain: a quantitative autoradiographic study

DR Gehlert, RC Speth, JK Wamsley - Neuroscience, 1986 - Elsevier
Angiotensin II receptors have been localized by quantitative autoradiography in the rat
central nervous system after labeling with [125 I] angiotensin II. A highly discrete distribution …

Cerebrospinal fluid angiotensin II immunoreactivity is not derived from the plasma.

H Mikami, H Suzuki, RR Smeby, CM Ferrario - Hypertension, 1985 - Am Heart Assoc
To elucidate whether the presence of angiotensin II immunoreactivity (ANG II-ir) in the
cerebrospinal fluid (CSF) of the dog is in part due to passage of the peptide across the CSF …

Quantitative distribution of angiotensin II binding sites in rat brain by autoradiography

JM Saavedra, A Israel, LM Plunkett, M Kurihara… - Peptides, 1986 - Elsevier
Angiotensin II binding sites were localized and quantified in individual brain nuclei from
single rats by incubation of tissue sections with 1 nM 125 I-[Sar 1]-angiotensin II,[3 H] …

Angiotensin II receptor localization in the canine CNS

RC Speth, JK Wamsley, DR Gehlert, CL Chernicky… - Brain Research, 1985 - Elsevier
Specific binding of [125 I] angiotensin II ([125 I] Ang II) to sections of dog brain was
determined by in vitro receptor autoradiography. Highly discrete, dark images representing …