The identification of new diagnostic, prognostic, or theranostics biomarkers is one of the
main aims of clinical research. Technologies like mass spectrometry (MS) focus on the …

Background: Mass spectrometry (MS) coupled to liquid chromatography (LC) represents a
widely used analytical tool for studying proteins, and discovering various diseases …

Reversed‐phase liquid chromatography (RPLC) is the most frequently used LC method for
separation of small molecule biomarkers, as well as peptides released by proteolytic …

As a potent quantitative and qualitative analytical technique, LC-MS/MS is useful in many
fields, including toxicology, endocrinology, paediatrics, microbiology, therapeutic drug …

Standard technology for analyte detection in clinical chemistry fields rely on indirect
characteristics of an analyte, eg its absorption capability of light, chemical reactivity or …

Mass spectrometry (MS)-based proteomics has become an indispensable tool with broad
applications in systems biology and biomedical research. With recent advances in liquid …

In this review we will give an overview of the issues related to biomarker discovery studies
with a focus on liquid chromatography-mass spectrometry (LC-MS) methods. Biomarker …

Liquid chromatography coupled to mass spectrometry (LC–MS/MS) is increasingly used as
a routine methodology in clinical laboratories for the analysis of low molecular weight …

Mass spectrometry (MS) in combination with liquid chromatography (LC), ie LC-MS, is the
key analytical technique on which the emerging “omics” technologies of proteomics …

The use of modern mass spectroscopy methods has made proteomics a promising new tool
for the clinical diagnosis of cancer and other diseases. Because body fluids like plasma …