The ability to engineer synthetic polymers with the same structural precision as
biomacromolecules is crucial to enable the de novo design of robust nanomaterials with …

Rational design of supramolecular nanomaterials fundamentally depends upon an atomic-
level understanding of their structure and how it responds to chemical modifications. Here …

Peptoids are a family of sequence-defined, non-natural biomimetic polymers which show
excellent properties including good chemical and enzymatic stability and high structural …

The design and synthesis of protein-like polymers is a fundamental challenge in materials
science. A biomimetic approach is to explore the impact of monomer sequence on non …

Sequence-defined peptoids, or N-substituted glycines, are an attractive class of bioispired
polymer due to their biostability and efficient synthesis. However, the de novo design of …

We explore strategies to enhance conformational ordering of N-substituted glycine peptoid
oligomers. Peptoids bearing bulky N-alkyl side chains have previously been studied as …

Peptoid polymers with sequence-defined side chains are observed to self-assemble into a
variety of structures spanning nanometer and micron scales. We explored a diblock …

The relationship between the structure of sequence-defined peptoid polymers and their
ability to assemble into well-defined nanostructures is important to the creation of new …

Protein mimics such as peptoids form self-assembled nanostructures whose shape and
function are governed by the side chain chemistry and secondary structure. Experiments …

Peptoids (N-substituted glycines) are a group of highly controllable peptidomimetic
polymers. Amphiphilic diblock peptoids have been engineered to assemble crystalline …