Exosome derived from human umbilical cord mesenchymal stem cell mediates MiR-181c attenuating burn-induced excessive inflammation

X Li, L Liu, J Yang, Y Yu, J Chai, L Wang, L Ma… - EBioMedicine, 2016 - thelancet.com
Mesenchymal stem cell (MSC)-derived exosomes have diverse functions in regulating
wound healing and inflammation; however, the molecular mechanism of human umbilical …

Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate IL-6-induced acute liver injury through miR-455-3p

M Shao, Q Xu, Z Wu, Y Chen, Y Shu, X Cao… - Stem cell research & …, 2020 - Springer
Background Using a toxin-induced nonhuman primate model of acute liver failure (ALF), we
previously reported that peripheral infusion of human umbilical cord mesenchymal stem …

Mesenchymal stem cell-derived exosomes containing miR-145-5p reduce inflammation in spinal cord injury by regulating the TLR4/NF-κB signaling pathway

Z Jiang, J Zhang - Cell Cycle, 2021 - Taylor & Francis
EXs (Exosomes) secreted by mesenchymal stem cells (MSCs) have the potential to treat
spinal cord injury (SCI), this study aimed to further explore the therapeutic effect of EXs on …

Exosomal miR-451 from human umbilical cord mesenchymal stem cells attenuates burn-induced acute lung injury

JS Liu, J Du, X Cheng, XZ Zhang, Y Li… - Journal of the Chinese …, 2019 - journals.lww.com
Background: The aim of this study was to investigate the molecular mechanism of human
umbilical cord mesenchymal stem cells (MSCs)-derived exosomes (hUCMSC-Exos) in …

Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulate regenerative wound healing via transforming growth factor-β receptor …

Y Zhang, Y Pan, Y Liu, X Li, L Tang, M Duan… - Stem cell research & …, 2021 - Springer
Background Scar formation is a common consequence of skin wound healing, and no
effective treatment exists. Umbilical cord blood mesenchymal stem cells (UCB-MSCs) can …

MicroRNA-21-3p engineered umbilical cord stem cell-derived exosomes inhibit tendon adhesion

Z Yao, J Li, X Wang, S Peng, J Ning… - Journal of …, 2020 - Taylor & Francis
Purpose As a common complication of tendon injury, tendon adhesion is an unresolved
problem in clinical work. The aim of this study was to investigate whether human umbilical …

MiR‐20a‐containing exosomes from umbilical cord mesenchymal stem cells alleviates liver ischemia/reperfusion injury

L Zhang, Y Song, L Chen, D Li, H Feng… - Journal of cellular …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been proved to exert considerable therapeutic effects
on ischemia‐reperfusion (I/R)‐induced injury, but the underlying mechanism remains …

Exosomes with high level of miR-181c from bone marrow-derived mesenchymal stem cells inhibit inflammation and apoptosis to alleviate spinal cord injury

M Zhang, L Wang, S Huang, X He - Journal of molecular histology, 2021 - Springer
Stem cell transplantation is a promising method in the treatment of spinal cord injury (SCI).
Researches have shown that stem cell-derived exosomes as well as its contents such as …

hucMSC-derived exosomes attenuate colitis by regulating macrophage pyroptosis via the miR-378a-5p/NLRP3 axis

X Cai, Z Zhang, J Yuan, DKW Ocansey, Q Tu… - Stem cell research & …, 2021 - Springer
Background Human umbilical cord mesenchymal stem cell (hucMSC)-derived exosomes
are recognized as novel cell-free therapeutic agents for inflammatory bowel disease (IBD), a …

hucMSC derived exosomes promote functional recovery in spinal cord injury mice via attenuating inflammation

G Sun, G Li, D Li, W Huang, R Zhang, H Zhang… - Materials Science and …, 2018 - Elsevier
The exploration of effective spinal cord injury (SCI) healing still remain a great challenge
due to the high morbidity, complex pathology and unclear targets. Human umbilical cord …