Deep learning-based emulation of human cardiac activation sequences

A Bertrand, J Camps, V Grau, B Rodriguez - International Conference on …, 2023 - Springer
The vision of digital twins for precision cardiology is to combine expert knowledge and data
of patients' cardiac pathophysiology with advanced computational methods, in order to …

Deep computational model for the inference of ventricular activation properties

L Li, J Camps, A Banerjee, M Beetz… - … Workshop on Statistical …, 2022 - Springer
Patient-specific cardiac computational models are essential for the efficient realization of
precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can …

Cardiac Digital Twin Pipeline for Virtual Therapy Evaluation

J Camps, ZJ Wang, R Doste, M Holmes… - arXiv preprint arXiv …, 2024 - arxiv.org
Cardiac digital twins are computational tools capturing key functional and anatomical
characteristics of patient hearts for investigating disease phenotypes and predicting …

Hyper-EP: Meta-learning hybrid personalized models for cardiac electrophysiology

X Jiang, S Vadhavkar, Y Ye, M Toloubidokhti… - arXiv preprint arXiv …, 2024 - arxiv.org
Personalized virtual heart models have demonstrated increasing potential for clinical use,
although the estimation of their parameters given patient-specific data remain a challenge …

[HTML][HTML] Inference of ventricular activation properties from non-invasive electrocardiography

J Camps, B Lawson, C Drovandi, A Minchole… - Medical Image …, 2021 - Elsevier
The realisation of precision cardiology requires novel techniques for the non-invasive
characterisation of individual patients' cardiac function to inform therapeutic and diagnostic …

Digital twinning of cardiac electrophysiology models from the surface ECG: a geodesic backpropagation approach

T Grandits, J Verhülsdonk, G Haase… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
The eikonal equation has become an indispensable tool for modeling cardiac electrical
activation accurately and efficiently. In principle, by matching clinically recorded and eikonal …

Towards the development of virtual heart technology for creating digital twins of cardiac electrophysiology

MAF Gsell, L Azzolin, KK Gillette, A Neic… - 2023 Computing in …, 2023 - ieeexplore.ieee.org
Introduction: Virtual heart technologies (VHTs) promise to offer an detailed view on cardiac
electrophysiology (EP). However, only very few VHTs simulating EP of four-chamber hearts …

Whole-heart electromechanical simulations using Latent Neural Ordinary Differential Equations

M Salvador, M Strocchi, F Regazzoni… - NPJ Digital …, 2024 - nature.com
Cardiac digital twins provide a physics and physiology informed framework to deliver
personalized medicine. However, high-fidelity multi-scale cardiac models remain a barrier to …

EP-Net: learning cardiac electrophysiology models for physiology-based constraints in data-driven predictions

I Ayed, N Cedilnik, P Gallinari, M Sermesant - Functional Imaging and …, 2019 - Springer
Cardiac electrophysiology (EP) models achieved good pro gress in simulating cardiac
electrical activity. However numerical issues and computational times hamper clinical …

Branched Latent Neural Operators

M Salvador, AL Marsden - arXiv preprint arXiv:2308.02599, 2023 - arxiv.org
We introduce Branched Latent Neural Operators (BLNOs) to learn input-output maps
encoding complex physical processes. A BLNO is defined by a simple and compact …