[HTML][HTML] Vimentin on the move: new developments in cell migration

RA Battaglia, S Delic, H Herrmann, NT Snider - F1000Research, 2018 - ncbi.nlm.nih.gov
The vimentin gene (VIM) encodes one of the 71 human intermediate filament (IF) proteins,
which are the building blocks of highly ordered, dynamic, and cell type-specific fiber …

Signaling pathways and protein–protein interaction of vimentin in invasive and migration cells: A review

DH Karoii, H Azizi, M Amirian - Cellular reprogramming, 2022 - liebertpub.com
The vimentin (encoded by VIM) is one of the 70 human intermediate filaments (IFs), building
highly dynamic and cell-type-specific web networks in the cytoplasm. Vim−/− mice exhibit …

Novel functions of vimentin in cell adhesion, migration, and signaling

J Ivaska, HM Pallari, J Nevo, JE Eriksson - Experimental cell research, 2007 - Elsevier
Vimentin is the major intermediate filament (IF) protein of mesenchymal cells. It shows
dynamically altered expression patterns during different developmental stages and high …

Roles of vimentin in health and disease

KM Ridge, JE Eriksson, M Pekny… - Genes & …, 2022 - genesdev.cshlp.org
More than 27 yr ago, the vimentin knockout (Vim−/−) mouse was reported to develop and
reproduce without an obvious phenotype, implying that this major cytoskeletal protein was …

Mechanical and non‐mechanical functions of filamentous and non‐filamentous vimentin

AE Patteson, A Vahabikashi, RD Goldman… - …, 2020 - Wiley Online Library
Intermediate filaments (IFs) formed by vimentin are less understood than their cytoskeletal
partners, microtubules and F‐actin, but the unique physical properties of IFs, especially their …

[HTML][HTML] Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition

MG Mendez, SI Kojima, RD Goldman - The FASEB Journal, 2010 - ncbi.nlm.nih.gov
Vimentin is used widely as a marker of the epithelial to mesenchymal transitions (EMTs) that
take place during embryogenesis and metastasis, yet the functional implications of the …

Vimentin as an integral regulator of cell adhesion and endothelial sprouting

JM Dave, KJ Bayless - Microcirculation, 2014 - Wiley Online Library
Angiogenesis is a multistep process that requires intricate changes in cell shape to generate
new blood vessels. IF are a large family of proteins that play an important structural and …

Vimentin fibers orient traction stress

N Costigliola, L Ding, CJ Burckhardt… - Proceedings of the …, 2017 - National Acad Sciences
The intermediate filament vimentin is required for cells to transition from the epithelial state
to the mesenchymal state and migrate as single cells; however, little is known about the …

Expression of vimentin alters cell mechanics, cell-cell adhesion, and gene expression profiles suggesting the induction of a hybrid EMT in human mammary epithelial …

S Sivagurunathan, A Vahabikashi, H Yang… - Frontiers in cell and …, 2022 - frontiersin.org
Vimentin is a Type III intermediate filament (VIF) cytoskeletal protein that regulates the
mechanical and migratory behavior of cells. Its expression is considered to be a marker for …

Impact of vimentin on regulation of cell signaling and matrix remodeling

Z Ostrowska-Podhorodecka, I Ding… - Frontiers in Cell and …, 2022 - frontiersin.org
Vimentin expression contributes to cellular mechanoprotection and is a widely recognized
marker of fibroblasts and of epithelial-mesenchymal transition. But it is not understood how …