Recent Advances in Fluorescent Theranostics for Alzheimer's Disease: A Comprehensive Survey on Design, Synthesis, and Properties
TN Francisco, D Malafaia, L Melo, AMS Silva… - ACS …, 2024 - ACS Publications
Alzheimer's disease (AD) is the most common form of neurodegenerative dementia that is
rapidly becoming a major health problem, especially in developed countries because of …
rapidly becoming a major health problem, especially in developed countries because of …
Shedding light on Alzheimer's disease: Recent advances in highly selective fluorescent probes
J Liu, Y Li, F Wang - Coordination Chemistry Reviews, 2025 - Elsevier
Alzheimer's disease (AD) is the predominant neurodegenerative disorder, affecting
approximately 60–80% of all patients diagnosed with dementia globally. Given the intricate …
approximately 60–80% of all patients diagnosed with dementia globally. Given the intricate …
Near-infrared fluorescent probes as imaging and theranostic modalities for amyloid-beta and tau aggregates in Alzheimer's disease
A person suspected of having Alzheimer's disease (AD) is clinically diagnosed for the
presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in …
presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in …
From Imaging Agents to Theranostic Drugs in Alzheimer's Disease
ML Bolognesi - Comprehensive Medicinal Chemistry III, 2017 - cris.unibo.it
The diagnosis of Alzheimer's disease (AD) took a major step forward in 2012, as Food and
Drug Administration approved the first positron emission tomography tracer. In parallel to …
Drug Administration approved the first positron emission tomography tracer. In parallel to …
Near‐Infrared Aggregation‐Induced Emission Luminogens for In Vivo Theranostics of Alzheimer's Disease
T Zhang, X Chen, C Yuan, X Pang… - Angewandte Chemie …, 2023 - Wiley Online Library
Optimized theranostic strategies for Alzheimer's disease (AD) remain almost absent from
bench to clinic. Current probes and drugs attempting to prevent β‐amyloid (Aβ) fibrosis …
bench to clinic. Current probes and drugs attempting to prevent β‐amyloid (Aβ) fibrosis …
Development of phenothiazine-based theranostic compounds that act both as inhibitors of β-amyloid aggregation and as imaging probes for amyloid plaques in …
P Dao, F Ye, Y Liu, ZY Du, K Zhang… - ACS chemical …, 2017 - ACS Publications
Early detection of Alzheimer's disease (AD) is imperative in enabling the understanding and
clinical treatment of this disorder, as well as in preventing its progression. Imaging agents …
clinical treatment of this disorder, as well as in preventing its progression. Imaging agents …
[HTML][HTML] Small-molecule theranostics in Alzheimer's disease
Á Sarabia-Vallejo, P López-Alvarado… - European Journal of …, 2023 - Elsevier
Alzheimer's Disease (AD) remains one of the most challenging health-related issues for our
society. It is becoming increasingly prevalent, especially in developed countries, due to the …
society. It is becoming increasingly prevalent, especially in developed countries, due to the …
Fluorescent Organic Molecules as Diagnostic and Theranostic Tools for Alzheimer's Disease
K Imran, YA Dhamapurkar, A Sharma - Natural Product-based Synthetic …, 2023 - Springer
Diagnosis of Alzheimer's disease (AD) is crucial especially for the complete comprehension
of pathology and clinical therapy of the disorder, as well as in declining the severity of the …
of pathology and clinical therapy of the disorder, as well as in declining the severity of the …
[HTML][HTML] Engineering of donor-acceptor-donor curcumin analogues as near-infrared fluorescent probes for in vivo imaging of amyloid-β species
Near-infrared (NIR) fluorescent imaging of both soluble and insoluble Aβ species in the
brain of Alzheimer's disease (AD) is crucial for the early diagnosis and intervention of AD. To …
brain of Alzheimer's disease (AD) is crucial for the early diagnosis and intervention of AD. To …
Frontiers in probing Alzheimer's disease biomarkers with fluorescent small molecules
Alzheimer's disease (AD) is the most common form of dementia. The pathogenesis of the
disease is associated with aggregated amyloid-β, hyperphosphorylated tau, a high level of …
disease is associated with aggregated amyloid-β, hyperphosphorylated tau, a high level of …