Transcription factors (TFs) regulate the expression of genes through sequence-specific
interactions with DNA-binding sites. However, despite recent progress in identifying in vivo …

Abstract Background Transcription factors (TFs) play a central role in regulating gene
expression by interacting with cis-regulatory DNA elements associated with their target …

Transcriptional regulation is largely enacted by transcription factors (TFs) binding DNA.
Large numbers of TF binding motifs have been revealed by ChIP-chip experiments followed …

ABSTRACT JASPAR (http://jaspar. genereg. net) is the leading open-access database of
matrix profiles describing the DNA-binding patterns of transcription factors (TFs) and other …

Binding of transcription factors (TFs) to regulatory sequences is a pivotal step in the control
of gene expression. Despite many advances in the characterization of sequence motifs …

The yeast Saccharomyces cerevisiae is a prevalent system for the analysis of transcriptional
networks. As a result, multiple DNA-binding sequence specificities (motifs) have been …

Transcription factors (TFs) interact with specific DNA regulatory sequences to control gene
expression throughout myriad cellular processes. However, the DNA binding specificities of …

Comprehensive identification of DNA cis-regulatory elements is crucial for a predictive
understanding of transcriptional network dynamics. Strong evidence suggests that these …

Since the advent of microarrays, vast amounts of gene expression data have been
generated. However, these microarray data fail to reveal the transcription regulatory …

Although the proteins that read the gene regulatory code, transcription factors (TFs), have
been largely identified, it is not well known which sequences TFs can recognize. We have …