Self‐assembling peptide as a potential carrier for hydrophobic anticancer drug ellipticine: complexation, release and in vitro delivery
The self‐assembling peptide EAK16‐II is capable of stabilizing hydrophobic compounds to
form microcrystal suspensions in aqueous solution. Here, the ability of this peptide to …
form microcrystal suspensions in aqueous solution. Here, the ability of this peptide to …
[HTML][HTML] Sequence Effect of Self-Assembling Peptides on the Complexation and In Vitro Delivery of the Hydrophobic Anticancer Drug Ellipticine
A special class of self-assembling peptides has been found to be capable of stabilizing the
hydrophobic anticancer agent ellipticine in aqueous solution. Here we study the effect of …
hydrophobic anticancer agent ellipticine in aqueous solution. Here we study the effect of …
Self-assembling peptide-based nanoparticles enhance anticancer effect of ellipticine in vitro and in vivo
Y Wu, P Sadatmousavi, R Wang, S Lu… - International journal …, 2012 - Taylor & Francis
Background and methods Applications of the anticancer agent, ellipticine, have been limited
by its hydrophobicity and toxicity. An efficient delivery system is required to exploit the …
by its hydrophobicity and toxicity. An efficient delivery system is required to exploit the …
Release of hydrophobic anticancer drug from a newly designed self-assembling peptide
M Wu, Z Ye, Y Liu, B Liu, X Zhao - Molecular BioSystems, 2011 - pubs.rsc.org
A newly designed self-assembling peptide, P4 (Ac-NH-LDLKLELKLDLKLELK-CONH2),
capable of stabilizing hydrophobic compounds in aqueous solution has been discovered …
capable of stabilizing hydrophobic compounds in aqueous solution has been discovered …
Molecular binding of self-assembling peptide EAK16-II with anticancer agent EPT and its implication in cancer cell inhibition
The current drug delivery techniques involve encapsulation, targeting and controlled release
of the drug with various molecules or nanoparticles, but rarely has the drug molecular state …
of the drug with various molecules or nanoparticles, but rarely has the drug molecular state …
Self-assembling peptide-based nanoparticles enhance cellular delivery of the hydrophobic anticancer drug ellipticine through caveolae-dependent endocytosis
A special class of self-assembling peptide (EAK16-II) has been found to stabilize the
hydrophobic anticancer agent ellipticine (EPT) in aqueous solution. In this study, the …
hydrophobic anticancer agent ellipticine (EPT) in aqueous solution. In this study, the …
Formation of colloidal suspension of hydrophobic compounds with an amphiphilic self-assembling peptide
The amphiphilic self-assembling peptide EAK16-II was found to be able to stabilize
hydrophobic compounds in aqueous solution. Micro/nanocrystals of a hydrophobic …
hydrophobic compounds in aqueous solution. Micro/nanocrystals of a hydrophobic …
Histidine-rich cell-penetrating peptide for cancer drug delivery and its uptake mechanism
In this work, we report a drug delivery system based on the pH-responsive self-assembly
and-disassembly behaviors of peptides. Here, a systematically designed histidine-rich …
and-disassembly behaviors of peptides. Here, a systematically designed histidine-rich …
Self-assembly mechanism of a peptide-based drug delivery vehicle
We report the mechanism of the concentration-dependent self-assembly of a tetrapeptide.
Peptide Boc-Trp-Leu-Trp-Leu-OMe self-assembles to form discrete nanospheres at a low …
Peptide Boc-Trp-Leu-Trp-Leu-OMe self-assembles to form discrete nanospheres at a low …
Self-assembling peptide as a potential carrier of hydrophobic compounds
C Keyes, J Duhamel, SY Fung, J Bezaire… - Journal of the …, 2004 - ACS Publications
Microcrystals of a hydrophobic cargo were stabilized by EAK16 II, a self-assembling
oligopeptide, and suspended in aqueous solution. Pyrene was used as a model …
oligopeptide, and suspended in aqueous solution. Pyrene was used as a model …