Immune boosting by B. 1.1. 529 (Omicron) depends on previous SARS-CoV-2 exposure

CJ Reynolds, C Pade, JM Gibbons, AD Otter, KM Lin… - Science, 2022 - science.org
The Omicron, or Pango lineage B. 1.1. 529, variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and …

Omicron BA. 1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes

J Quandt, A Muik, N Salisch, BG Lui, S Lutz… - Science …, 2022 - science.org
Omicron is the evolutionarily most distinct severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variant of concern (VOC) to date. We report that Omicron BA. 1 breakthrough …

Omicron BA. 2 breakthrough infection enhances cross-neutralization of BA. 2.12. 1 and BA. 4/BA. 5

A Muik, BG Lui, M Bacher, AK Wallisch, A Toker… - Science …, 2022 - science.org
BNT162b2-vaccinated individuals after Omicron BA. 1 breakthrough infection have strong
serum-neutralizing activity against Omicron BA. 1, BA. 2, and previous SARS-CoV-2 variants …

[HTML][HTML] Repeated vaccination of inactivated SARS-CoV-2 vaccine dampens neutralizing antibodies against Omicron variants in breakthrough infection

B Gao, L He, Y Bao, Y Chen, G Lu, Y Zhang, Y Xu… - Cell Research, 2023 - nature.com
Dear Editor, Since the emergence of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) in 2019, the virus has continued to evolve resulting in new waves of infection …

Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variants

TS Johnston, SH Li, MM Painter, RK Atkinson… - Immunity, 2024 - cell.com
The spike glycoprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
continues to accumulate substitutions, leading to breakthrough infections of vaccinated …

[HTML][HTML] Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant

Y Gao, C Cai, A Grifoni, TR Müller, J Niessl… - Nature medicine, 2022 - nature.com
The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Omicron (B. 1.1. 529) variant of concern (VOC) has destabilized global efforts to control the …

Neutralization of Omicron sublineages and Deltacron SARS-CoV-2 by three doses of BNT162b2 vaccine or BA. 1 infection

C Kurhade, J Zou, H Xia, M Liu, Q Yang… - Emerging microbes & …, 2022 - Taylor & Francis
ABSTRACT Distinct SARS-CoV-2 Omicron sublineages have evolved showing increased
fitness and immune evasion than the original Omicron variant BA. 1. Here, we report the …

SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients

D Geers, MC Shamier, S Bogers, G den Hartog… - Science …, 2021 - science.org
The emergence of SARS-CoV-2 variants harboring mutations in the spike (S) protein has
raised concern about potential immune escape. Here, we studied humoral and cellular …

Omicron sub-lineages BA. 4/BA. 5 escape BA. 1 infection elicited neutralizing immunity

K Khan, F Karim, Y Ganga, M Bernstein, Z Jule… - MedRxiv, 2022 - medrxiv.org
The SARS-CoV-2 Omicron (B. 1.1. 529) variant first emerged as the BA. 1 sub-lineage, with
extensive escape from neutralizing immunity elicited by previous infection with other …

[HTML][HTML] Continued evasion of neutralizing antibody response by Omicron XBB. 1.16

JN Faraone, P Qu, YM Zheng, C Carlin, D Jones… - Cell reports, 2023 - cell.com
The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues
to challenge the efficacy of vaccination efforts against coronavirus disease 2019 (COVID …