[HTML][HTML] Artificial cell synthesis using biocatalytic polymerization-induced self-assembly

A Belluati, S Jimaja, RJ Chadwick, C Glynn… - Nature Chemistry, 2024 - nature.com
Artificial cells are biomimetic microstructures that mimic functions of natural cells, can be
applied as building blocks for molecular systems engineering, and host synthetic biology …

Synthetic control of living cells by intracellular polymerization

O Baghdasaryan, S Khan, JC Lin, J Lee-Kin… - Trends in …, 2024 - cell.com
An emerging cellular engineering method creates synthetic polymer matrices inside cells. By
contrast with classical genetic, enzymatic, or radioactive techniques, this materials-based …

Polymer hydrogel capsules: en route toward synthetic cellular systems

B Städler, AD Price, R Chandrawati, L Hosta-Rigau… - Nanoscale, 2009 - pubs.rsc.org
Engineered synthetic cellular systems are expected to become a powerful biomedical
platform for the development of next-generation therapeutic carrier vehicles. In this mini …

Synthesizing biomaterials in living organisms

X Zhang, J Wang, Y Zhang, Z Yang, J Gao… - Chemical Society …, 2023 - pubs.rsc.org
Living organisms fabricate biomacromolecules such as DNA, RNA, and proteins by the self-
assembly process. The research on the mechanism of biomacromolecule formation also …

Cell-specific integration of artificial organelles based on functionalized polymer vesicles

N Ben-Haim, P Broz, S Marsch, W Meier… - Nano letters, 2008 - ACS Publications
Cell organelles are subcellular structures characterized by specific functionalities. They
often consist of membrane-delineated microcompartments with a unique set of enzymes …

Programmed self-assembly of hierarchical nanostructures through protein–nanoparticle coengineering

R Mout, G Yesilbag Tonga, LS Wang, M Ray, T Roy… - ACS …, 2017 - ACS Publications
Hierarchical organization of macromolecules through self-assembly is a prominent feature in
biological systems. Synthetic fabrication of such structures provides materials with emergent …

Biotemplated synthesis of inorganic materials: An emerging paradigm for nanomaterial synthesis inspired by nature

BA Krajina, AC Proctor, AP Schoen… - Progress in Materials …, 2018 - Elsevier
Biomineralization, the process by which biological systems direct the synthesis of inorganic
structures from organic templates, is an exquisite example of nanomaterial self-assembly in …

Actinosomes: condensate-templated containers for engineering synthetic cells

KA Ganar, L Leijten, S Deshpande - ACS synthetic biology, 2022 - ACS Publications
Engineering synthetic cells has a broad appeal, from understanding living cells to designing
novel biomaterials for therapeutics, biosensing, and hybrid interfaces. A key prerequisite to …

Bottom-up tissue engineering

DL Elbert - Current opinion in biotechnology, 2011 - Elsevier
Recapitulating the elegant structures formed during development is an extreme synthetic
and biological challenge. Great progress has been made in developing materials to support …

Synthetic biology for protein-based materials

ZG Qian, F Pan, XX Xia - Current Opinion in Biotechnology, 2020 - Elsevier
Highlights•Synthetic biology serves as an engine for the creation of advanced protein
materials.•Diverse structural, functional and responsive building blocks were …