[HTML][HTML] Total Flavonoids of Glycyrrhiza uralensis Alleviates Irinotecan-Induced Colitis via Modification of Gut Microbiota and Fecal Metabolism
SJ Yue, YF Qin, A Kang, HJ Tao, GS Zhou… - Frontiers in …, 2021 - frontiersin.org
Irinotecan (CPT-11)-induced gastrointestinal toxicity strongly limits its anticancer efficacy.
Glycyrrhiza uralensis Fisch., especially flavonoids, has strong anti-inflammatory and …
Glycyrrhiza uralensis Fisch., especially flavonoids, has strong anti-inflammatory and …
Insight into the mechanism of Xiao–Chai–Hu–Tang alleviates irinotecan-induced diarrhea based on regulating the gut microbiota and inhibiting Gut β-GUS
C Wang, X Teng, C Wang, B Liu, R Zhou, X Xu, H Qiu… - Phytomedicine, 2023 - Elsevier
Abstract Background Irinotecan (CPT-11, Camptosar@) is a first-line drug for metastatic
colorectal cancer. CPT-11-induced diarrhea, which is closely related to the concentrations of …
colorectal cancer. CPT-11-induced diarrhea, which is closely related to the concentrations of …
Glycyrrhiza uralensis Fisch. alleviates dextran sulfate sodium-induced colitis in mice through inhibiting of NF-κB signaling pathways and modulating intestinal …
G Shi, J Kong, Y Wang, Z Xuan, F Xu - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Licorice is widely used in traditional Chinese Medicine
(TCM) for compound compatibility, which could reduce toxicity and increase efficacy of …
(TCM) for compound compatibility, which could reduce toxicity and increase efficacy of …
[HTML][HTML] Astragalin attenuates dextran sulfate sodium (DSS)-induced acute experimental colitis by alleviating gut microbiota dysbiosis and inhibiting NF-κB activation …
L Peng, X Gao, L Nie, J Xie, T Dai, C Shi, L Tao… - Frontiers in …, 2020 - frontiersin.org
With the ulcerative colitis (UC) incidence increasing worldwide, it is of great importance to
prevent and treat UC. However, efficient treatment options for UC are relatively limited. Due …
prevent and treat UC. However, efficient treatment options for UC are relatively limited. Due …
[HTML][HTML] Fructus ligustri lucidi suppresses inflammation and restores the microbiome profile in murine colitis models
W Yu, S Sun, K Zhang, H Li, M Xin, Y Liu, J Yan - Phytomedicine, 2022 - Elsevier
Background Ulcerative colitis (UC) is pathologically characterized by an inappropriate
immune response to the gut commensal microbes accompanied by persistent epithelial …
immune response to the gut commensal microbes accompanied by persistent epithelial …
[HTML][HTML] Grape seed proanthocyanidin alleviates intestinal inflammation through gut microbiota-bile acid crosstalk in mice
Y Wu, R Mo, M Zhang, W Zhou, D Li - Frontiers in Nutrition, 2022 - frontiersin.org
Regulation of gut microbiota and modulation of bile acid (BA) composition are potential
strategies for the treatment of intestinal inflammation. This study aimed to investigate the …
strategies for the treatment of intestinal inflammation. This study aimed to investigate the …
[HTML][HTML] Kaempferol alleviates murine experimental colitis by restoring gut microbiota and inhibiting the LPS-TLR4-NF-κB axis
Y Qu, X Li, F Xu, S Zhao, X Wu, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Intestinal microbiota dysbiosis is an established characteristic of ulcerative colitis (UC).
Regulating the gut microbiota is an attractive alternative UC treatment strategy, considering …
Regulating the gut microbiota is an attractive alternative UC treatment strategy, considering …
Impact of Lycium barbarum arabinogalactan on the fecal metabolome in a DSS-induced chronic colitis mouse model
C Cao, L Wang, C Ai, G Gong, Z Wang, L Huang… - Food & Function, 2022 - pubs.rsc.org
Ulcerative colitis (UC) is often accompanied by the dysbiosis of gut microbiota and
metabolism. Our previous study indicated that arabinogalactan from Lycium barbarum (LBP …
metabolism. Our previous study indicated that arabinogalactan from Lycium barbarum (LBP …
Rhubarb Peony Decoction ameliorates ulcerative colitis in mice by regulating gut microbiota to restoring Th17/Treg balance
S Luo, R Wen, Q Wang, Z Zhao, F Nong, Y Fu… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacology relevance Rhubarb Peony Decoction (RPD) is a formula of
traditional Chinese medicine chronicled in Jin Gui Yao Lve, commonly used to treat …
traditional Chinese medicine chronicled in Jin Gui Yao Lve, commonly used to treat …
Dehydrocostus lactone alleviates irinotecan-induced intestinal mucositis by blocking TLR4/MD2 complex formation
M Sun, H Zhan, X Long, AM Alsayed, Z Wang, F Meng… - Phytomedicine, 2024 - Elsevier
Abstract Background Irinotecan (CPT-11) is used as chemotherapeutic drug for treatment of
colorectal cancer. However, without satisfactory treatments, its gastrointestinal toxicities such …
colorectal cancer. However, without satisfactory treatments, its gastrointestinal toxicities such …