Neuropathic pain is a debilitating form of chronic pain resulting from nerve injury, disease
states, or toxic insults. Neuropathic pain is often refractory to conventional …

Cannabis extracts and synthetic cannabinoids are still widely considered illegal substances.
Preclinical and clinical studies have suggested that they may result useful to treat diverse …

This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …

Although cannabinoids have anti-hyperalgesic effects in animal models of nerve injury,
there are currently very few prospective trials of the efficacy of cannabinoids in neuropathic …

Objective: To review the literature concerning the physiology of the endocannabinoid
system, current drug development of cannabinoid agonists, and current clinical research on …

The President of the International Association for the Study of Pain established a task force
on cannabis and cannabinoid analgesia to systematically examine the evidence on (1) …

The endocannabinoid system, consisting of the cannabinoid 1 receptor (CB 1 R) and
cannabinoid 2 receptor (CB 2 R), endogenous cannabinoid ligands (endocannabinoids) …

Neuropathic pain is a worldwide epidemic that occurs in 3 to 8% of individuals in
industrialized countries and is often refractory to existing treatments. Drugs currently …

Recent advances have dramatically increased our understanding of cannabinoid
pharmacology: the psychoactive constituents of Cannabis sativa have been isolated …

This article reviews recent research on cannabinoid analgesia via the endocannabinoid
system and non-receptor mechanisms, as well as randomized clinical trials employing …