Background: C3 glomerulopathy (C3G), a rare glomerular disease mediated by alternative
complement pathway dysregulation, is associated with a high rate of recurrence and graft …

Rationale & Objective C3 glomerulopathy (C3G), a form of glomerulonephritis associated
with dysregulation of the alternative complement pathway, occurs either as dense deposit …

The C3 glomerulopathies are a group of rare kidney diseases characterized by complement
dysregulation occurring in the fluid phase and in the glomerular microenvironment, which …

Abstract Background C3 Glomerulopathy (C3G) is a rare glomerular disease caused by
dysregulation of the complement pathway. Based on its pathophysiology, treatment with the …

The complement system is part of innate immunity and is pivotal in protecting the body
against pathogens and maintaining host homeostasis. Activation of the complement system …

Abstract C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of
the alternative complement pathway in plasma and the glomerular microenvironment. The …

Abstract Background C3 glomerulopathy (C3G) is a rare, but severe glomerular disease with
grim prognosis. The complex pathogenesis is just unfolding, and involves acquired as well …

Abstract C3 glomerulonephritis (C3GN) results from abnormalities in the alternative pathway
of complement, and it is characterized by deposition of C3 with absent or scant Ig deposition …

Background Cases reports and small series of patients with C3 glomerulopathy have
reported variable efficacy of eculizumab. Study Design Case series of C3 glomerulopathy …

C3 glomerulopathy (C3G) is a rare set of kidney diseases with 2 patterns: C3
glomerulonephritis (C3GN) and dense deposit disease. Pathogenesis of both diseases is …