Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

F Ahmed, LT Vu, H Zhu, DSH Iu, EA Fogarty, Y Kwak… - BioRxiv, 2022 - biorxiv.org
SUMMARY ME/CFS is a serious and poorly understood disease. To understand immune
dysregulation in ME/CFS, we used single-cell RNA-seq (scRNA-seq) to examine immune …

Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

LT Vu, F Ahmed, H Zhu, DSH Iu, EA Fogarty… - Cell Reports …, 2024 - cell.com
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious and poorly
understood disease. To understand immune dysregulation in ME/CFS, we use single-cell …

Whole blood human transcriptome and virome analysis of ME/CFS patients experiencing post-exertional malaise following cardiopulmonary exercise testing

J Bouquet, T Li, JL Gardy, X Kang, S Stevens… - PloS one, 2019 - journals.plos.org
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a syndrome of unknown
etiology characterized by profound fatigue exacerbated by physical activity, also known as …

Distinct plasma immune signatures in ME/CFS are present early in the course of illness

M Hornig, JG Montoya, NG Klimas, S Levine… - Science …, 2015 - science.org
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is an unexplained
incapacitating illness that may affect up to 4 million people in the United States alone. There …

Longitudinal cytokine and multi-modal health data of an extremely severe ME/CFS patient with HSD reveals insights into immunopathology, and disease severity

F Jahanbani, JC Sing, RD Maynard… - Frontiers in …, 2024 - frontiersin.org
Introduction Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) presents
substantial challenges in patient care due to its intricate multisystem nature, comorbidities …

Stress-induced transcriptomic changes in females with myalgic encephalomyelitis/chronic fatigue syndrome reveal disrupted immune signatures

DJ Van Booven, J Gamer, A Joseph, M Perez… - International Journal of …, 2023 - mdpi.com
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic, complex multi-
organ illness characterized by unexplained debilitating fatigue and post-exertional malaise …

Sex-dependent transcriptional changes in response to stress in patients with myalgic encephalomyelitis/chronic fatigue syndrome: a pilot project

J Gamer, DJ Van Booven, O Zarnowski… - International Journal of …, 2023 - mdpi.com
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, multi-symptom
illness characterized by debilitating fatigue and post-exertional malaise (PEM). Numerous …

[HTML][HTML] A molecular network approach reveals shared cellular and molecular signatures between chronic fatigue syndrome and other fatiguing illnesses

PH Comella, E Gonzalez-Kozlova, R Kosoy… - medRxiv, 2021 - ncbi.nlm.nih.gov
The molecular mechanisms of chronic fatigue syndrome (CFS, or Myalgic
encephalomyelitis), a disease defined by extreme, long-term fatigue, remain largely …

Autoimmune gene expression profiling of fingerstick whole blood in Chronic Fatigue Syndrome

Z Wang, MF Waldman, TJ Basavanhally… - Journal of Translational …, 2022 - Springer
Abstract Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a
debilitating condition that can lead to severe impairment of physical, psychological …

Peripheral immune landscape for hypercytokinemia in myasthenic crisis utilizing single-cell transcriptomics

H Zhong, X Huan, R Zhao, M Su, C Yan, J Song… - Journal of Translational …, 2023 - Springer
Background Myasthenia gravis (MG) is the most prevalent autoimmune disorder affecting
the neuromuscular junction. A rapid deterioration in respiratory muscle can lead to a …