Intensive risk factor management and cardiovascular autonomic neuropathy in type 2 diabetes: the ACCORD trial

Y Tang, H Shah, CR Bueno Junior, X Sun… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE The effects of preventive interventions on cardiovascular autonomic neuropathy
(CAN) remain unclear. We examined the effect of intensively treating traditional risk factors …

Cardiovascular autonomic neuropathy and cardiovascular outcomes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and …

R Pop-Busui, BH Braffett, B Zinman, C Martin… - Diabetes …, 2017 - Am Diabetes Assoc
OBJECTIVE To examine whether cardiovascular autonomic neuropathy (CAN) is an
independent risk factor of cardiovascular disease (CVD) events during DCCT/EDIC …

Effects of cardiac autonomic dysfunction on mortality risk in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial

R Pop-Busui, GW Evans, HC Gerstein… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE Intensive therapy targeting normal blood glucose increased mortality compared
with standard treatment in a randomized clinical trial of 10,251 participants with type 2 …

[HTML][HTML] Diabetic cardiovascular autonomic neuropathy predicts recurrent cardiovascular diseases in patients with type 2 diabetes

SA Cha, JS Yun, TS Lim, K Min, KH Song, KD Yoo… - PLoS …, 2016 - journals.plos.org
Cardiovascular autonomic neuropathy (CAN) is a risk factor for cardiovascular disease
(CVD) and mortality in patients with type 2 diabetes. This study evaluated the relationship …

Risk factors for the presence and progression of cardiovascular autonomic neuropathy in type 2 diabetes: ADDITION-Denmark

ST Andersen, DR Witte, J Fleischer, H Andersen… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE To examine the course of cardiovascular autonomic neuropathy (CAN) and
related cardiometabolic risk factors in patients with type 2 diabetes. RESEARCH DESIGN …

[HTML][HTML] Progression of cardiovascular autonomic neuropathy and cardiovascular disease in type 2 diabetes

JS Yun, YM Park, SA Cha, YB Ahn, SH Ko - Cardiovascular diabetology, 2018 - Springer
Background To examine whether the progression rate of cardiovascular autonomic
neuropathy (CAN) stage is an independent predictive factor for cardiovascular disease …

[HTML][HTML] Neuropathy: the crystal ball for cardiovascular disease?

AI Vinik, RE Maser, D Ziegler - Diabetes care, 2010 - ncbi.nlm.nih.gov
Cardiovascular disease (CVD) is a ma-jor cause of death in patients with type 2 diabetes.
Unclear, however, is the effect of intensive therapy in reducing the development of …

What do we know and we do not know about cardiovascular autonomic neuropathy in diabetes

R Pop-Busui - Journal of cardiovascular translational research, 2012 - Springer
Cardiovascular autonomic neuropathy (CAN) in diabetes is generally overlooked in practice,
although awareness of its serious consequences is emerging. Challenges in understanding …

Risk factors for diabetic peripheral neuropathy and cardiovascular autonomic neuropathy in the Diabetes Control and Complications Trial/Epidemiology of Diabetes …

BH Braffett, RA Gubitosi-Klug, JW Albers… - Diabetes, 2020 - Am Diabetes Assoc
The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and
Complications (DCCT/EDIC) study demonstrated that intensive glucose control reduced the …

[HTML][HTML] Risk factors for cardiac autonomic neuropathy in type 1 diabetes mellitus

DR Witte, S Tesfaye, N Chaturvedi, SEM Eaton… - Diabetologia, 2005 - Springer
Aims/hypothesis Cardiac autonomic neuropathy (CAN) is associated with increased
morbidity and mortality in type 1 diabetes. Apart from glycaemic control, risk factors for CAN …