The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

The worldwide obesity epidemic has become a major health concern, because it contributes
to higher mortality due to an increased risk for noncommunicable diseases including …

Obesity is a worldwide epidemic with multiple obesity-associated health problems including
type 2 diabetes, hypertension, and cardiovascular disease. Adipose tissue serves as a fuel …

Chronic inflammation has been linked with an increased risk of type 2 diabetes and
cardiovascular disease. As an endocrine and inflammatory organ, adipose tissue is an …

Adiposity‐associated inflammation and insulin resistance are strongly implicated in the
development of type 2 diabetes and atherosclerotic cardiovascular disease. This article …

Advances in adipose tissue biology over the past 10 years have led to an improved
understanding of the mechanisms linking obesity with the metabolic syndrome and other …

Several lines of preclinical and clinical research have confirmed that chronic low-grade
inflammation of adipose tissue is mechanistically linked to metabolic disease and organ …

Chronic inflammation constitutes an important link between obesity and its
pathophysiological sequelae. In contrast to the belief that inflammatory signals exert a …

Adipose tissue is a complex organ that comprises a wide range of cell types with diverse
energy storage, metabolic regulation, and neuroendocrine and immune functions. Because …

Weight gain and obesity are major risk factors for conditions and diseases ranging from
insulin resistance and type 2 diabetes mellitus to atherosclerosis and the sequelae of …