[HTML][HTML] Neuroprotective therapies in the NICU in preterm infants: present and future (Neonatal Neurocritical Care Series)

EJ Molloy, M El-Dib, J Soul, S Juul, AJ Gunn… - Pediatric …, 2024 - nature.com
The survival of preterm infants has steadily improved thanks to advances in perinatal and
neonatal intensive clinical care. The focus is now on finding ways to improve morbidities …

Optimizing neurodevelopmental outcomes after prematurity: lessons in neuroprotection and early intervention.

SC Bauer, ME Msall - Minerva pediatrica, 2010 - europepmc.org
In recent decades, advances in maternal-fetal, obstetrics, and neonatal medicine have led to
the increased survival of preterm infants. Very preterm infants (< 32 weeks gestation), who …

Neuroprotection strategies in preterm encephalopathy

P Parikh, SE Juul - Seminars in pediatric neurology, 2019 - Elsevier
Advances in neonatology have led to unprecedented improvements in neonatal survival
such that those born as early as 22 weeks of gestation now have some chance of survival …

Acute symptomatic neonatal seizures, brain injury, and long-term outcome: the role of neuroprotective strategies

F Pisani, C Fusco, L Nagarajan… - Expert review of …, 2021 - Taylor & Francis
Introduction Neonatal seizures are frequent but underdiagnosed manifestations of acute
brain dysfunction and an important contributor to unfavorable outcomes. Etiology and …

Protecting the premature brain: current evidence-based strategies for minimising perinatal brain injury in preterm infants

CL Lea, A Smith-Collins, K Luyt - Archives of Disease in Childhood-Fetal …, 2017 - fn.bmj.com
Improving neurodevelopmental outcome for preterm infants is an important challenge for
neonatal medicine. The disruption of normal brain growth and neurological development is …

Update on mechanisms of the pathophysiology of neonatal encephalopathy

JO Davidson, F Gonzalez, P Gressens, AJ Gunn… - Seminars in Fetal and …, 2021 - Elsevier
Therapeutic hypothermia is now well established to significantly improve survival without
disability after neonatal encephalopathy (NE). To further improve outcomes, we need to …

Brain damage in the preterm infant: Clinical aspects and recent progress in the prevention and treatment

Y Xie, Y Yang, T Yuan - … (Formerly Current Drug Targets-CNS & …, 2023 - ingentaconnect.com
Although the prevalence of brain injury and related neurodevelopmental disabilities
resulting from preterm birth are major public health concerns, there are no definite …

Neuroscience meets nurture: challenges of prematurity and the critical role of family-centred and developmental care as a key part of the neuroprotection care bundle

R Soni, CT Wel-Wel, NJ Robertson - … of Disease in Childhood-Fetal and …, 2022 - fn.bmj.com
Advances in neonatal–perinatal medicine have resulted in increased survival at lower
gestations. Although the incidence of germinal matrix haemorrhage-intraventricular …

Neuroprotection of the preterm brain

B Fleiss, P Gressens - Handbook of clinical neurology, 2019 - Elsevier
Despite notable advances in the care and survival of preterm infants, a significant proportion
of preterm neonates will have life-long cognitive, behavioral, and motor deficits, and robustly …

Pharmacologic neuroprotective strategies in neonatal brain injury

SE Juul, DM Ferriero - Clinics in perinatology, 2014 - perinatology.theclinics.com
The two most common causes of neonatal brain injury in the United States are extreme
prematurity and hypoxic-ischemic encephalopathy (HIE). In the United States, 1 in 8 babies …