Non-flavonoid polyphenols in osteoporosis: Preclinical evidence

D Bellavia, F Caradonna, E Dimarco, V Costa… - Trends in Endocrinology …, 2021 - cell.com
The development of progressive osteopenia and osteoporosis (OP) is due to the imbalance
between bone resorption and bone formation, determining a lower bone resistance, major …

Flavonoids in bone erosive diseases: perspectives in osteoporosis treatment

D Bellavia, E Dimarco, V Costa, V Carina… - Trends in Endocrinology …, 2021 - cell.com
Imbalance of bone homeostasis, with excessive bone resorption compared with bone
formation, leads to the development of progressive osteopenia leading to lower bone …

Analysis of the molecular mechanisms by flavonoids with potential use for osteoporosis prevention or therapy

V Rodríguez, M Rivoira, G Picotto… - Current Medicinal …, 2022 - ingentaconnect.com
Background: Osteoporosis is the most common skeletal disorder worldwide. Flavonoids
have the potential to alleviate bone alterations in osteoporotic patients with the advantage of …

Polyphenols as potential preventers of osteoporosis: A comprehensive review on antioxidant and anti-inflammatory effects, molecular mechanisms, and signal …

Z Su, B Yao, G Liu, J Fang - The Journal of Nutritional Biochemistry, 2023 - Elsevier
Osteoporosis (OP) is a skeletal disorder characterized by decreased bone density,
alterations in bone microstructure, and increased damage to the bones. As the population …

[HTML][HTML] Molecular signaling mechanisms behind polyphenol-induced bone anabolism

E Torre - Phytochemistry reviews, 2017 - Springer
For millennia, in the different cultures all over the world, plants have been extensively used
as a source of therapeutic agents with wide-ranging medicinal applications, thus becoming …

Phenolic phytochemicals and bone

V Habauzit, MN Horcajada - Phytochemistry Reviews, 2008 - Springer
Concerning the prevention of osteoporosis, recognized as a major public health problem,
nutrition may appear as an alternative strategy for optimizing health skeleton. The …

The effects of flavonoids on bone

AA Welch, AC Hardcastle - Current osteoporosis reports, 2014 - Springer
Osteoporosis and fragility fractures are a growing problem for our aging population with
around 1 in 2 women and 1 in 5 men suffering from an osteoporotic fracture during their …

[HTML][HTML] Flavonoids: classification, function, and molecular mechanisms involved in bone remodelling

P Ramesh, R Jagadeesan, S Sekaran… - Frontiers in …, 2021 - frontiersin.org
Flavonoids are polyphenolic compounds spotted in various fruits, vegetables, barks, tea
plants, and stems and many more natural commodities. They have a multitude of …

Naturally plant-derived compounds: role in bone anabolism

MN Horcajada, E Offord - Current molecular pharmacology, 2012 - ingentaconnect.com
From a nutritional point of view, several factors are involved in ensuring optimal bone health.
The most documented of these are calcium and vitamin D. However, it is now well …

[HTML][HTML] Modulatory effects of plant polyphenols on bone remodeling: a prospective view from the bench to bedside

V Nicolin, N De Tommasi, SL Nori… - Frontiers in …, 2019 - frontiersin.org
During the past, a more comprehensive knowledge of mechanisms implicated in bone
resorption processes has driven researchers to develop a compound library of many small …