Ovarian immature teratomas (OITs) are malignant tumors originating from the ovarian germ
cells that mainly occur during the first 30 y of a female's life. Early age of onset strongly …

Premature ovarian failure (POF) is an unexplained amenorrhoea (> 6 months) with raised
levels of gonadotropins (FSH> 40 U/L) occurring before the age of 40 years. Recent studies …

Background Premature ovarian insufficiency (POI) occurs in women before the age of 40
years, accompanied by amenorrhea, hypoestrogenism, hypergonadotropinism, and …

Background Bone morphogenetic protein 15 (BMP15) is expressed in oocytes and plays a
crucial role in the reproduction of mono-ovulating species. In humans, BMP15 gene …

Abstract Bone morphogenetic protein 15 (BMP15) encodes an oocyte factor with a relevant
role for folliculogenesis as homodimer or cumulin heterodimer (BMP15‐GDF9) …

BACKGROUND Bone morphogenetic protein 15 (BMP15) is an oocyte-derived growth factor
acting as a major player in follicle differentiation in mammals. Mutations in the BMP15 gene …

BMP15 has drawn particular attention in the pathophysiology of reproduction, as its
mutations in mammalian species have been related to different reproductive phenotypes. In …

Premature ovarian failure (POF), also known as premature menopause, is defined as at
least six months of amenorrhea before the age of 40 with elevated gonadotrophins and …

Abstract Bone morphogenetic protein‐15 (BMP15) is selectively synthesized by oocytes as a
pre‐proprotein and is considered an ovarian follicle organizer whose adequate function is …

Context: Premature ovarian failure (POF) is a cause of female infertility characterized by
primary (PA) or secondary amenorrhea (SA) and elevated gonadotropins. The pathogenesis …